Evidence map›Paper›PMID 32835295›Full record

ReviewBrain, behavior, & immunity - health2020

Cerebrovascular disease in COVID-19: Is there a higher risk of stroke?

Marcos Altable, Juan Moisés de la Serna

Open access · goldAbstract readReview
In one paragraph

Review in Brain, behavior, & immunity - health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Stroke in COVID-19: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2021
    Pooled it
  2. Extracellular Vesicles: The Invisible Heroes and Villains of COVID-19 Central Neuropathology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  3. Review
  4. Review
  5. COVID-19 independently predicts poor outcomes in Acute Ischemic Stroke- Insights from a multicenter study from Pakistan and United Arab Emirates.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Down's syndrome and COVID-19: risk or protection factor against infection? A molecular and genetic approach.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. A COVID-19-Related Retinopathy Case Report.Case reports in ophthalmology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marcos AltablePrivate Practice of Neurology, Neuroceuta. (Virgen de África Clinic), Ceuta, Spain.
Juan Moisés de la SernaDepartment of Education, International University of La Rioja (UNIR), Madrid, Spain.
Universidad de La Rioja · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of stroke has been observed in young adults (under fifty years of age) without cardiovascular risk factors who are suffering from COVID-19. It is speculated that there is really a significant increase, as a few cases have yet to be described, or that the infection favors his development. Cerebrovascular events are more common in older patients with stroke risk factors, such as hypertension and diabetes mellitus, and those who have elevated fibrin D-dimers. Multiple case reports and series about cerebrovascular disease (CVD) in COVID-19 has been informed. The mechanism that causes cerebral ischemia in COVID-19 remains undiscovered. However, progressively there is increasing evidence of hypercoagulability that can be or contribute to the cause. We review the current literature about CVD both epidemiology and etiology. More studies are needed to understand.

Indexed as

Cerebrovascular diseaseCOVID-19EndothelitisHipercoagulabilityStrokeYoung

Identifiers

PMID32835295
PMCPMC7297683
OpenAlexW3031863397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.