Evidence map›Paper›PMID 32835273›Full record

ArticleJACC. Case reports2020

Safety and Efficacy of Amiodarone in a Patient With COVID-19.

Nadia Castaldo, Alberto Aimo, Vincenzo Castiglione, Cristiano Padalino, Michele Emdin, Carlo Tascini

Open access · goldAbstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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  5. COVID-19 health policy evaluation: integrating health and economic perspectives with a data envelopment analysis approach.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nadia CastaldoAzienda Sanitaria Integrata del Friuli Centrale, Udine, Italy.
Alberto AimoInstitute of Life Science, Scuola Sant'Anna Pisa, Pisa, Italy.
Vincenzo CastiglioneInstitute of Life Science, Scuola Sant'Anna Pisa, Pisa, Italy.
Cristiano PadalinoAzienda Sanitaria Integrata del Friuli Centrale, Udine, Italy.
Michele EmdinInstitute of Life Science, Scuola Sant'Anna Pisa, Pisa, Italy.
Carlo TasciniAzienda Sanitaria Integrata del Friuli Centrale, Udine, Italy.
Ospedale Santa Maria della Misericordia di Udine · ITAzienda Ospedaliera Universitaria Pisana · ITFondazione Toscana Gabriele Monasterio · ITScuola Superiore Sant'Anna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an urgent need for effective treatments for coronavirus disease-2019 (COVID-19). Amiodarone, like hydroxychloroquine, exerts antiviral actions by interfering with endocytosis and viral replication. Here, to our knowledge, we report the first case of a patient affected by respiratory failure related to COVID-19 who recovered after only supportive measures and a short amiodarone course. (

Indexed as

amiodaroneCAD, cationic amphiphilic drugCOVID-19COVID-19, coronavirus disease-2019SARS-CoV-2SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2

Identifiers

PMID32835273
PMCPMC7259916
OpenAlexW3031923561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.