Evidence map›Paper›PMID 32835231›Full record

ArticleCanine medicine and genetics2020

Lifespan of companion dogs seen in three independent primary care veterinary clinics in the United States.

Silvan R Urfer, Matt Kaeberlein, Daniel E L Promislow, Kate E Creevy

Open access · goldAbstract read
In one paragraph

Article in Canine medicine and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 56 citations in OpenAlex.

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  17. Dog and owner demographics impact dietary choices in Dog Aging Project cohort.Journal of the American Veterinary Medical Association · 2024
    Article
  18. How can we achieve more accurate reporting of average dog lifespan?Journal of the American Veterinary Medical Association · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Silvan R UrferDog Aging Project, Department of Pathology, University of Washington School of Medicine, Seattle, WA USA.ORCID 0000-0002-3722-0731
Matt KaeberleinDog Aging Project, Department of Pathology, University of Washington School of Medicine, Seattle, WA USA.
Daniel E L PromislowDog Aging Project, Department of Pathology, University of Washington School of Medicine, Seattle, WA USA.
Kate E CreevyDog Aging Project, Department of Pathology, University of Washington School of Medicine, Seattle, WA USA.
University of Washington · US

Funding

The Dog Aging Project: Genetic and Environmental Determinants of Healthy Aging in Companion Dogs Competitive RevisionU19AG057377 · NIA · UNIVERSITY OF WASHINGTON · PI KEENE, CHRISTOPHER DIRK, PROMISLOW, DANIEL EDWARD · 2018 to 2023
$29.0M
The Domestic Dog as a Model System for Aging ResearchR24AG044284 · NIA · UNIVERSITY OF WASHINGTON · PI PROMISLOW, DANIEL EDWARD · 2013 to 2015
$419k
NIA NIH HHS R24 AG044284NIA NIH HHS U19 AG057377
6 · The paper itself

Abstract

backgroundThe privately owned companion dog is an emerging model in comparative medicine, notably because it shares the human environment including its risk factors, is affected by many analogous age-related diseases, receives comparable medical care, and has excellent veterinary medical data available.Past studies of dog lifespan have used academic, corporate or insurance data. While independent primary care data exist for the UK, none have as of yet been published for the US. This study analyzed data from three independent primary care US veterinary hospitals and identified factors that influence lifespan and mortality in a cohort of

resultsAs previously reported, body size was negatively correlated with lifespan. Gonadectomy was associated with a longer lifespan, with the effect being stronger in females than in males. This lifespan advantage was conserved in gonadectomized female dogs that lived to at least ages 5 and 8 years. We did not find significant differences in lifespan between purebred and mixed breed dogs; however, breeds with larger effective population sizes and/or lower inbreeding coefficients had median survival times 3-6 months longer than breeds with smaller effective population sizes or higher inbreeding coefficients, indicating that these measures of genetic diversity may be affecting breed lifespans. We also found that dog breeds belonging to the "Mountain" ancestral group had median survival times that were 3.5-4.6 years shorter than other purebred dog groups, which remained significant even when correcting for body size.

conclusionsOur findings show that it is possible to obtain and analyze data from independent veterinary clinics in the US, an approach that could be useful for studies of comparative epidemiology under the

Indexed as

DogsEpidemiologyEpizootiologyHealthspanInbreedingLife spanLifespanOne healthOne welfareSurvival analysisVeterinary medicine

Identifiers

PMID32835231
PMCPMC7386164
OpenAlexW3035377671

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.