Evidence map›Paper›PMID 32835228›Full record

ArticleCanine medicine and genetics2020

Polymorphisms in the

Alisdair M Boag, Andrea Short, Lorna J Kennedy, Hattie Syme, Peter A Graham, Brian Catchpole

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canine medicine and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alisdair M BoagPathobiology and Population Sciences, The Royal Veterinary College, University of London, London, UK.ORCID 0000-0002-3819-1821
Andrea ShortCentre for Integrated Genomic Medical Research, University of Manchester, Manchester, UK.
Lorna J KennedyCentre for Integrated Genomic Medical Research, University of Manchester, Manchester, UK.
Hattie SymeClinical Science and Services, The Royal Veterinary College, University of London, London, UK.
Peter A GrahamFaculty of Medicine & Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Brian CatchpolePathobiology and Population Sciences, The Royal Veterinary College, University of London, London, UK.
University of London · GBUniversity of Manchester · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCanine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison's disease in humans. Several dog breeds are overrepresented in the disease population, suggesting that a genetic component is involved, although this is likely to be polygenic. Previous research has implicated

resultsPolymorphisms in the CTLA4 promoter were determined by PCR and sequence-based typing. There were significant associations with three promoter haplotypes in cocker spaniels (

conclusionsThis study provides further evidence that

Indexed as

Addison’sCanineCTLA-4HypoadrenocorticismPromoter

Identifiers

PMID32835228
PMCPMC7371821
OpenAlexW3021149103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.