Evidence map›Paper›PMID 32834475›Full record

ArticleApplied mathematics letters2021

Simulating the spread of COVID-19

Alex Viguerie, Guillermo Lorenzo, Ferdinando Auricchio, Davide Baroli, Thomas J R Hughes, Alessia Patton, Alessandro Reali, Thomas E Yankeelov, Alessandro Veneziani

Abstract read
In one paragraph

Article in Applied mathematics letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. On quasi-linear reaction diffusion systems arising from compartmental SEIR models.Nonlinear differential equations and applications : NoDEA · 2024
    Article
  5. Heterogeneous risk tolerance, in-groups, and epidemic waves.Frontiers in applied mathematics and statistics · 2024
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  6. Article
  7. Article
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  9. A two-phase fluid model for epidemic flow.Infectious Disease Modelling · 2023
    Article
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  11. Article
  12. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alex ViguerieDipartimento di Ingegneria Civile ed Architettura, Università di Pavia, Via Ferrata 3, Pavia, PV 27100, Italy.
Guillermo LorenzoOden Institute for Computational Engineering and Sciences, The University of Texas at Austin, 201 E. 24th Street, Austin, TX 78712-1229, USA.
Ferdinando AuricchioDipartimento di Ingegneria Civile ed Architettura, Università di Pavia, Via Ferrata 3, Pavia, PV 27100, Italy.
Davide BaroliAachen Institute for Advanced Study in Computational Engineering Science (AICES), RWTH Aachen University, Schinkelstraße 2, 52062 Aachen, Germany.
Thomas J R HughesOden Institute for Computational Engineering and Sciences, The University of Texas at Austin, 201 E. 24th Street, Austin, TX 78712-1229, USA.
Alessia PattonDipartimento di Ingegneria Civile ed Architettura, Università di Pavia, Via Ferrata 3, Pavia, PV 27100, Italy.
Alessandro RealiDipartimento di Ingegneria Civile ed Architettura, Università di Pavia, Via Ferrata 3, Pavia, PV 27100, Italy.
Thomas E YankeelovDepartments of Biomedical Engineering, Diagnostic Medicine, and Oncology, Livestrong Cancer Institutes, The University of Texas at Austin, 107 W. Dean Keeton St., Austin, TX 78712, USA.
Alessandro VenezianiDepartment of Mathematics, Emory University, 400 Dowman Drive, Atlanta, GA 30322, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present an early version of a Susceptible-Exposed-Infected-Recovered-Deceased (SEIRD) mathematical model based on partial differential equations coupled with a heterogeneous diffusion model. The model describes the spatio-temporal spread of the COVID-19 pandemic, and aims to capture dynamics also based on human habits and geographical features. To test the model, we compare the outputs generated by a finite-element solver with measured data over the Italian region of Lombardy, which has been heavily impacted by this crisis between February and April 2020. Our results show a strong qualitative agreement between the simulated forecast of the spatio-temporal COVID-19 spread in Lombardy and epidemiological data collected at the municipality level. Additional simulations exploring alternative scenarios for the relaxation of lockdown restrictions suggest that reopening strategies should account for local population densities and the specific dynamics of the contagion. Thus, we argue that data-driven simulations of our model could ultimately inform health authorities to design effective pandemic-arresting measures and anticipate the geographical allocation of crucial medical resources.

Indexed as

Compartmental modelsCOVID-19Mathematical biologyMathematical epidemiologyMathematical modelingPartial differential equations

Identifiers

PMID32834475
PMCPMC7361091

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.