Evidence map›Paper›PMID 32833935›Full record

Trial reportMedical care2020

Racial Differences in the Effectiveness of a Multifactorial Telehealth Intervention to Slow Diabetic Kidney Disease.

Elizabeth A Kobe, Clarissa J Diamantidis, Hayden B Bosworth, Clemontina A Davenport, Megan Oakes, Anastasia-Stefania Alexopoulos, Jane Pendergast, Uptal D Patel, Matthew J Crowley

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Education programmes for people with chronic kidney disease and diabetes.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  3. Pooled it
  4. Trial
  5. Addressing Unmet Needs in the Management of Chronic Kidney Disease.International journal of general medicine · 2026
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Elizabeth A KobeDuke University School of Medicine.
Clarissa J DiamantidisDepartment of Population Health Sciences.
Hayden B BosworthDepartment of Population Health Sciences.
Clemontina A DavenportBiostatistics and Bioinformatics.
Megan OakesDepartment of Medicine, Division of General Internal Medicine.
Anastasia-Stefania AlexopoulosDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Change (ADAPT).
Jane PendergastBiostatistics and Bioinformatics.
Uptal D PatelDepartment of Medicine, Division of Nephrology, Duke University School of Medicine.
Matthew J CrowleyDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Change (ADAPT).
Duke University · USGeneral Department of Preventive Medicine · VNInstitute of Behavioral Sciences · JP

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Endocrinology and Metabolism Training ProgramT32DK007012 · NIDDK · DUKE UNIVERSITY · PI DAVID A. D'ALESSIO · 1986 to 2026
$6.8M
Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI COFFMAN, THOMAS M · 2012 to 2016
$5.9M
NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
Multi-factorial Intervention to Slow Progression of Diabetic Kidney DiseaseR01DK093938 · NIDDK · DUKE UNIVERSITY · PI BOSWORTH, HAYDEN B, DIAMANTIDIS, CLARISSA JONAS · 2013 to 2017
$3.4M
Integrated Population Program for Diabetic Kidney DiseaseR34DK102166 · NIDDK · DUKE UNIVERSITY · PI BOSWORTH, HAYDEN B, BOULWARE, LEIGH E · 2014 to 2015
$711k
Is there a digital divide in Chronic Kidney Disease (CKD)?K23DK099385 · NIDDK · DUKE UNIVERSITY · PI DIAMANTIDIS, CLARISSA JONAS · 2014 to 2017
$678k
HSR&D Senior Research Career Scientist AwardIK6HX003161 · VA · DURHAM VA MEDICAL CENTER · PI Hayden B Bosworth · 2020 to 2026
–
HSRD VA CDA 13-261HSRD VA IK6 HX003161NCATS NIH HHS TL1 TR002555NCATS NIH HHS UL1 TR001117NCATS NIH HHS UL1 TR002553NIDDK NIH HHS K23 DK099385NIDDK NIH HHS P30 DK096493NIDDK NIH HHS R01 DK093938NIDDK NIH HHS R34 DK102166NIDDK NIH HHS T32 DK007012
6 · The paper itself

Abstract

backgroundAfrican Americans are significantly more likely than non-African Americans to have diabetes, chronic kidney disease, and uncontrolled hypertension, increasing their risk for kidney function decline.

objectiveThe objective of this study was to compare how African Americans and non-African Americans with diabetes responded to a multifactorial telehealth intervention designed to slow kidney function decline. RESEARCH

designSecondary analysis of a randomized trial. Primary care patients (N=281, 56% African American) were allocated to either: (1) a multifactorial, pharmacist-delivered phone-based telehealth intervention focused on behavioral and medication management of diabetic kidney disease; or (2) an education control. MEASURES: The primary study outcome was change in estimated glomerular filtration rate (eGFR). Linear mixed models were used to explore the moderating effect of race on the relationship between study arm and eGFR decline over time; the mean annual rate of eGFR decline was estimated by race and study arm.

resultsFindings demonstrated a differential intervention effect on kidney function over time by race (Pinteraction=0.005). Among African Americans, the intervention arm had significantly greater preservation of eGFR over time than the control arm (difference in the annual rate of eGFR decline=1.5 mL/min/1.73 m; 95% confidence interval: 0.04, 3.02). For non-African Americans, the intervention arm had a faster decline in eGFR over time than the control arm (difference in the annual rate of eGFR decline=-1.7 mL/min/1.73 m; 95% confidence interval: -3.3, -0.02).

conclusionA multifactorial, pharmacist-delivered telehealth intervention for diabetic kidney disease may be more effective for slowing eGFR decline among African Americans than non-African Americans.

Indexed as

Disease ManagementAdolescentAdultAgedBlack or African AmericanDiabetes Mellitus, Type 2Diabetic NephropathiesFemaleGlomerular Filtration RateHealth BehaviorHumansMaleMedication AdherenceMiddle AgedPatient Education as TopicPharmacists

Identifiers

PMID32833935
PMCPMC7572637
OpenAlexW3081391529

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.