Evidence map›Paper›PMID 32833484›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2020

Moderated mediation for exercise maintenance in pain and posttraumatic stress disorder: A randomized trial.

Erica R Scioli, Brian N Smith, James W Whitworth, Avron Spiro, Michael Esterman, Sunny Dutra, Kristina M Bogdan, Alex Eld, Ann M Rasmusson

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Erica R ScioliWomen's Health Sciences Division, National Center for PTSD, Research Service, VA Boston Healthcare System.ORCID 0000-0001-9250-5185
Brian N SmithWomen's Health Sciences Division, National Center for PTSD, Research Service, VA Boston Healthcare System.
James W WhitworthNational Center for PTSD, VA Boston Healthcare System.ORCID 0000-0001-7084-7774
Avron SpiroMassachusetts Veterans Epidemiology and Research Information Center (MAVERIC) VA Boston Healthcare System.
Michael EstermanVA Boston Healthcare System.
Sunny DutraClinical Psychology Department, William James College.
Kristina M BogdanWomen's Health Sciences Division, National Center for PTSD, Research Service, VA Boston Healthcare System.
Alex EldAffiliate of Women's Health Sciences Division, National Center for PTSD, Research Service, VA Boston Healthcare System.
Ann M RasmussonWomen's Health Sciences Division, National Center for PTSD, Research Service, VA Boston Healthcare System.ORCID 0000-0002-3488-9042
National Center for PTSD · USVA Boston Healthcare System · USWilliam James College · US

Funding

Postdoctoral Training Program in Stress and TraumaT32MH019836 · NIMH · TUFTS UNIVERSITY BOSTON · PI DENISE M. SLOAN · 1996 to 2026
$4.7M
Neurobiological Mediators of Self-Regulatory and Reward-Based Motivational Predictors of Exercise Maintenance in Chronic Pain and PTSDR21AT010293 · NCCIH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHECKO (SCIOLI), ERICA ROSE · 2018 to 2019
$347k
Defining biotypes of PTSD with resting-state connectivityI01CX001653 · VA · VA BOSTON HEALTH CARE SYSTEM · PI ESTERMAN, MICHAEL · 2018 to 2021
–
CSRD VA I01 CX001653Department of Veterans Affairs Clinical Sciences Research and DevelopmentNational Institutes of Health; Science of Behavior Change (SOBC) Common Fund ProgramNCCIH NIH HHS R21 AT010293NIMH NIH HHS T32 MH019836U.S. Department of Veterans Affairs; Clinical Science R&D Service
6 · The paper itself

Abstract

This study utilizes the Science of Behavior Change (SOBC) experimental medicine approach to evaluate the effects of a 3-month, individually prescribed progressive exercise training program on neurobiological, cognitive and motivational mechanisms by which our exercise-training paradigm may foster exercise maintenance. We will investigate hypothesized relationships between exercise-training associated augmentation of neuropeptide Y (NPY) system function and improvements in self-regulation and reward sensitivity-cognitive control and motivational processes posited to promote self-efficacy and intrinsic motivation, which have been shown to predict exercise maintenance. This study will recruit Veterans with chronic low back pain and posttraumatic stress disorder (PTSD). Procedures include a baseline, acute cardiopulmonary exercise challenge assessment that will inform the exercise prescription for a 12-week progressive exercise training program comprised of three 45-minute aerobic exercise sessions per week-all of which will be supervised by an exercise physiologist. Additionally, a week-7 and week-14 exercise challenge assessment will track changes in NPY system function and the variables of interest. We hypothesize that increases in the capacity to release NPY in response to acute exercise testing will be associated with improvements in self-regulation and reward sensitivity, which will in turn be associated with self-efficacy and intrinsic motivation to maintain regular exercise. Ninety participants will be randomized either to the "active exercise training condition" or to the "wait list symptom monitoring condition". The study aims to demonstrate the feasibility of procedures and elucidate mechanisms relevant to developing individually prescribed, motivationally based exercise regimens to reduce negative consequences of PTSD and low back pain over the long-term. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Indexed as

Exercise TherapyFemaleHumansMalePainProspective StudiesStress Disorders, Post-Traumatic

Identifiers

PMID32833484
PMCPMC8559731
OpenAlexW3080882589

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.