Evidence map›Paper›PMID 32833442›Full record

ArticleJournal of the American Chemical Society2020

Intrinsic and Extrinsic Programming of Product Chain Length and Release Mode in Fungal Collaborating Iterative Polyketide Synthases.

Chen Wang, Xiaojing Wang, Liwen Zhang, Qun Yue, Qingpei Liu, Ya-Ming Xu, A A Leslie Gunatilaka, Xiaoyi Wei, Yuquan Xu, István Molnár

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The divergence of DHN-derived melanin pathways in Metarhizium robertsii.World journal of microbiology & biotechnology · 2024
    Article
  6. Review
  7. Biosynthesis of Cytosporones in Leotiomycetous Filamentous Fungi.Journal of the American Chemical Society · 2024
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Chen WangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China.ORCID 0000-0001-8639-647X
Xiaojing WangMicrobial Pharmacology Laboratory, Shanghai University of Medicine and Health Sciences, 279 Zhouzhu Highway, Pudong New Area, Shanghai 201318, P. R. China.
Liwen ZhangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China.
Qun YueBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China.
Qingpei LiuSouthwest Center for Natural Products Research, University of Arizona, 250 East Valencia Road, Tucson, Arizona 85706, United States.
Ya-Ming XuSouthwest Center for Natural Products Research, University of Arizona, 250 East Valencia Road, Tucson, Arizona 85706, United States.
A A Leslie GunatilakaSouthwest Center for Natural Products Research, University of Arizona, 250 East Valencia Road, Tucson, Arizona 85706, United States.ORCID 0000-0001-9663-3600
Xiaoyi WeiKey Laboratory of Plant Resources Conservation and Sustainable Utilization/Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, P. R. China.ORCID 0000-0002-4053-6999
Yuquan XuBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China.
István MolnárSouthwest Center for Natural Products Research, University of Arizona, 250 East Valencia Road, Tucson, Arizona 85706, United States.ORCID 0000-0002-3627-0454
University of Arizona · USChinese Academy of Agricultural Sciences · CNBeijing Botanical Garden · CNShanghai University of Medicine and Health Sciences · CN

Funding

Combinatorial biosynthesis of fungal benzenediol lactone polyketidesR01GM114418 · NIGMS · UNIVERSITY OF ARIZONA · PI MOLNAR, ISTVAN · 2016 to 2019
$1.4M
NIGMS NIH HHS R01 GM114418
6 · The paper itself

Abstract

Combinatorial biosynthesis with fungal polyketide synthases (PKSs) promises to produce unprecedented bioactive "unnatural" natural products (uNPs) for drug discovery. Genome mining of the dothideomycete

Indexed as

AcyltransferasesAmino Acid SequenceAscomycotaBiosynthetic PathwaysCombinatorial Chemistry TechniquesFungal ProteinsModels, MolecularMultigene FamilyPhenylacetatesPolyketide SynthasesProtein ConformationSaccharomyces cerevisiaeThiolester HydrolasesAcyltransferasesFungal ProteinsPhenylacetatesphenylacetic acidPolyketide SynthasesThiolester Hydrolases

Identifiers

PMID32833442
PMCPMC7659983
OpenAlexW3081019927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.