Evidence map›Paper›PMID 32833317›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020

Pd-Catalyzed Directed Thiocyanation Reaction by C-H Bond Activation.

Mélissa Gao, Mu-Yi Chen, Xavier Pannecoucke, Philippe Jubault, Tatiana Besset

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Directed Palladium Catalyzed C-H (Ethoxycarbonyl)difluoromethylthiolation Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  3. Review
  4. Pd-Catalyzed Directed Thiocyanation Reaction by C-H Bond Activation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mélissa GaoNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.ORCID http://orcid.org/0000-0003-3141-2908
Mu-Yi ChenNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.ORCID http://orcid.org/0000-0002-6364-8715
Xavier PannecouckeNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.ORCID http://orcid.org/0000-0002-4598-7895
Philippe JubaultNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.ORCID http://orcid.org/0000-0002-3295-9326
Tatiana BessetNormandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000, Rouen, France.ORCID http://orcid.org/0000-0003-4877-5270

Funding

Agence Nationale de la Recherche ANR-11-LABX-0029Agence Nationale de la Recherche ANR-17-CE07-0038-01ERC 758710
6 · The paper itself

Abstract

The Pd-catalyzed directed thiocyanation reaction of arenes and heteroarenes by C-H bond activation was achieved. In the presence of an electrophilic SCN source, this original methodology offered an efficient tool to access a panel of functionalized thiocyanated compounds (21 examples, up to 78 % yield). Post-functionalization reactions further demonstrated the synthetic utility of the approach by converting the SCN-containing molecules into value-added scaffolds.

Indexed as

C−H activationhomogeneous catalysispalladiumsynthetic methodologythiocyanation

Identifiers

PMID32833317
PMCPMC7756308

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.