Evidence map›Paper›PMID 32833227›Full record

ArticleThe Journal of physiology2020

Tracking the motion of the K

Antonios Pantazis, Maki Kaneko, Marina Angelini, Federica Steccanella, Annie M Westerlund, Sarah H Lindström, Michelle Nilsson, Lucie Delemotte, Sulagna C Saitta, Riccardo Olcese

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The Journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. An epilepsy-associated KProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. A NovelInternational journal of molecular sciences · 2021
    Article
  10. Exploring KFrontiers in molecular biosciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Antonios PantazisDivision of Molecular Medicine, Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-6467-1327
Maki KanekoCenter for Personalized Medicine, Children's Hospital, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-2489-6185
Marina AngeliniDivision of Molecular Medicine, Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Federica SteccanellaDivision of Molecular Medicine, Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Annie M WesterlundScience for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, Solna, Sweden.ORCID 0000-0003-2288-5711
Sarah H LindströmDivision of Neurobiology, Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.ORCID 0000-0001-7952-8120
Michelle NilssonDivision of Neurobiology, Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
Lucie DelemotteScience for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, Solna, Sweden.
Sulagna C SaittaDepartment of Obstetrics and Gynecology and Division of Medical Genetics, Department of Pediatrics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Riccardo OlceseDivision of Molecular Medicine, Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-4225-9814
University of California, Los Angeles · USLinköping University · SEScience for Life Laboratory · SEChildren's Hospital of Los Angeles · US

Funding

The Late L-type Ca Current as the Target for a New Class of AntiarrhythmicsR01HL134346 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OLCESE, RICCARDO · 2017 to 2020
$2.3M
The Molecular Transitions that Initiate EC Coupling in Skeletal MuscleR35GM131896 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OLCESE, RICCARDO · 2019 to 2023
$2.0M
NHLBI NIH HHS R01 HL134346NIGMS NIH HHS R35 GM131896NIH/NHLBI R01HL134346NIH/NIGMS R35GM131896Postdoctoral Fellowship 17POST33670046Scientist Development 14SDG20300018
6 · The paper itself

Abstract

key pointsK ABSTRACT: An exome-based diagnostic panel in an infant with epilepsy revealed a previously unreported de novo missense variant in KCNA2, which encodes voltage-gated K

Indexed as

Brain DiseasesEpilepsyAmino Acid SubstitutionHumansMembrane PotentialsMutationchannelopathyepilepsyfluorometrygain of functionloss of functionmolecular dynamicspotassium channel

Identifiers

PMID32833227
PMCPMC8923147
OpenAlexW3081331366

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.