Evidence map›Paper›PMID 32833193›Full record

ArticleAIDS and behavior2021

Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach.

Sara N Levintow, Brian W Pence, Kimberly A Powers, Teerada Sripaipan, Tran Viet Ha, Viet Anh Chu, Vu Minh Quan, Carl A Latkin, Vivian F Go

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01689545 (Prevention for Positives), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01689545 nacompletednot on this map

Prevention for Positives: A Randomized Controlled Trial Among Vietnamese HIV-positive Injecting Drug Users

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2007 to 2013Enrolled2,175ConditionsHIVArmsIndividual level, Structural level, Individual level standard of care, Structural level standard of care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sara N LevintowDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB #7435, Chapel Hill, NC, 27599-743, USA. levintow@email.unc.edu.ORCID http://orcid.org/0000-0001-5558-526X
Brian W PenceDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB #7435, Chapel Hill, NC, 27599-743, USA.
Kimberly A PowersDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB #7435, Chapel Hill, NC, 27599-743, USA.
Teerada SripaipanDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Tran Viet HaUNC Project Vietnam, University of North Carolina, Hanoi, Vietnam.
Viet Anh ChuUNC Project Vietnam, University of North Carolina, Hanoi, Vietnam.
Vu Minh QuanCenters for Disease Control and Prevention, Atlanta, GA, USA.
Carl A LatkinDepartment of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Vivian F GoDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USCenters for Disease Control and Prevention · USJohns Hopkins University · US

Funding

Training in Infectious Disease Epidemiology (TIDE)T32AI070114 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Brian W Pence · 2007 to 2026
$4.0M
Prevention for Positives: A Randomized Controlled Trial Among Vietnamese HIV-PosiR01DA022962 · NIDA · JOHNS HOPKINS UNIVERSITY · PI GO, VIVIAN F. · 2007 to 2011
$3.1M
The role of depression in HIV transmission among people who inject drugs in VietnamR36DA045569 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEVINTOW, SARA NICOLE · 2018 to 2019
$150k
National Institute of Allergy and Infectious Diseases T32 AI070114-10NIAID NIH HHS T32 AI070114NIDA NIH HHS R01 DA022962NIDA NIH HHS R01 DA022962-01NIDA NIH HHS R36 DA045569ViiV Healthcare Pre-Doctoral Fellowship
6 · The paper itself

Abstract

The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009-2013. Study visits every 6 months over 2 years measured depressive symptoms in the past week and injecting and sexual behaviors in the prior 3 months. Severe depressive symptoms (vs. mild/no symptoms) increased injection equipment sharing (risk difference [RD] = 3.9 percentage points, 95% CI -1.7, 9.6) but not condomless sex (RD = -1.8, 95% CI -6.4, 2.8) as reported 6 months later. The cross-sectional association with injection equipment sharing at the same visit (RD = 6.2, 95% CI 1.4, 11.0) was stronger than the longitudinal effect. Interventions on depression among PWID may decrease sharing of injection equipment and the corresponding risk of HIV transmission.Clinical trial registration ClinicalTrials.gov NCT01689545.

Indexed as

HIV InfectionsSubstance Abuse, IntravenousAdultCross-Sectional StudiesDepressionHumansMaleMiddle AgedPharmaceutical PreparationsRisk-TakingVietnamYoung AdultPharmaceutical PreparationsDepressive symptomsHIV transmissionInjecting behaviorMarginal structural modelsPeople who inject drugsSexual behavior

Identifiers

PMID32833193
PMCPMC7444452
OpenAlexW3081480386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.