Evidence map›Paper›PMID 32833017›Full record

ArticleJAMA network open2020

Cardiopulmonary Resuscitation Preferences of People Receiving Dialysis.

Gwen M Bernacki, Ruth A Engelberg, J Randall Curtis, Manjula Kurella Tamura, Lyndia C Brumback, Danielle C Lavallee, Elizabeth K Vig, Ann M O'Hare

Erratum issued Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JAMA network open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05878171 (Preference of Life-Sustaining Treatment Among Patients With End Stage Renal Disease), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05878171 recruitingnot on this mapstarted 2023, after this paper: background citation

Preference of Life-Sustaining Treatment Among Patients With End Stage Renal Disease

TypeobservationalSponsorNational Taiwan University HospitalRan2023 to 2025Enrolled200ConditionsEnd Stage Renal Disease
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gwen M BernackiDepartment of Medicine, University of Washington, Seattle.
Ruth A EngelbergDepartment of Medicine, University of Washington, Seattle.
J Randall CurtisDepartment of Medicine, University of Washington, Seattle.
Manjula Kurella TamuraDepartment of Medicine, Stanford University Medical Center, Palo Alto, California.
Lyndia C BrumbackDepartment of Biostatistics, University of Washington, Seattle.
Danielle C LavalleeDepartment of Surgery, University of Washington, Seattle.
Elizabeth K VigDepartment of Medicine, University of Washington, Seattle.
Ann M O'HareDepartment of Medicine, University of Washington, Seattle.
University of Washington · USVA Puget Sound Health Care System · USStanford Medicine · US

Funding

Palliative Care Research Training GrantT32HL125195 · NHLBI · UNIVERSITY OF WASHINGTON · PI KROSS, ERIN KATHRYN, SHARMA, RASHMI K. · 2015 to 2024
$3.2M
USRDS Special Study Center on Palliative and End-of-Life CareU01DK102150 · NIDDK · UNIVERSITY OF WASHINGTON · PI KURELLA TAMURA, MANJULA, O'HARE, ANN M. · 2014 to 2018
$2.6M
NHLBI NIH HHS T32 HL125195
6 · The paper itself

Abstract

Importance: Whether the cardiopulmonary resuscitation (CPR) preferences of patients receiving dialysis align with their values and other aspects of end-of-life care is not known. Objective: To describe the CPR preferences of patients receiving dialysis and how these preferences are associated with their responses to questions about other aspects of end-of-life care. Design, Setting, and Participants: Cross-sectional survey study of a consecutive sample of patients receiving dialysis at 31 nonprofit dialysis facilities in 2 US metropolitan areas (Seattle, Washington, and Nashville, Tennessee) between April 22, 2015, and October 2, 2018. Analyses for this article were conducted between December 2018 and April 2020. Exposures: Participants were asked to respond to the question "If you had to decide right now, would you want CPR if your heart were to stop beating?" Those who indicated they would probably or definitely want CPR were categorized as preferring CPR. Main Outcomes and Measures: This study examined the association between preference for CPR and other treatment preferences, engagement in advance care planning, values, desired place of death, expectations about prognosis, symptoms, and palliative care needs. Results: Of the 1434 individuals invited to complete the survey, 1009 agreed to participate, and 876 were included in the analytic cohort (61.1%). The final cohort had a mean (SD) age of 62.6 (14.0) years; 492 (56.2%) were men, and 528 (60.3%) were White individuals. Among 738 of 876 participants (84.2%) who indicated that they would definitely or probably want CPR (CPR group), 555 (75.2%) wanted mechanical ventilation vs 13 of 138 (9.4%) of those who did not want CPR (do not resuscitate [DNR] group) (P < .001). A total of 249 of 738 participants (33.7%) in the CPR group vs 84 of 138 (60.9%) in the DNR group had documented treatment preferences (P < .001). In terms of values about future care, 171 participants (23.2%) in the CPR group vs 5 of 138 (3.6%) in the DNR group valued life prolongation (P < .001); 320 in the CPR group (43.4%) vs 109 of 138 in the DNR group (79.0%) valued comfort (P < .001); and 247 participants (33.5%) in the CPR group vs 24 of 138 (17.4%) in the DNR group were unsure about their wishes for future care (P < .001). In the CPR group, 207 (28.0%) had thought about stopping dialysis vs 62 of 138 (44.9%) in the DNR group (P < .001), and 181 (24.5%) vs 58 of 138 (42.0%) had discussed stopping dialysis (P = .001). No statistically significant associations were observed between CPR preference and documentation of a surrogate decision maker, thoughts or discussion of hospice, preferred place of death, expectations about prognosis, reported symptoms, or palliative care needs. Conclusions and Relevance: The CPR preferences of patients receiving dialysis were associated with some, but not all, other aspects of end-of-life care. How participants responded to questions about these other aspects of end-of-life care were not always aligned with their CPR preference. More work is needed to integrate discussions about code status with bigger picture conversations about patients' values, goals, and preferences for end-of-life care.

Indexed as

Renal DialysisAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPatient PreferenceResuscitation OrdersSurveys and QuestionnairesTennesseeTerminal CareWashington

Identifiers

PMID32833017
PMCPMC7445594
OpenAlexW3081183139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.