ArticleInvestigative ophthalmology & visual science2020
Effects of Narrowband Light on Choroidal Thickness and the Pupil.
Article in Investigative ophthalmology & visual science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05852782 (Effects of Narrowband and Broadband Light on Choroidal Thickness and Melanopsin-driven Pupil Response), which is not on this map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Narrowband and Broadband Light on Choroidal Thickness and Melanopsin-driven Pupil Response
Who cites it
38 citing papers in PubMed, 54 citations in OpenAlex.
- The Effect of Light Intensity and the Timing of Light Exposure on Choroidal Thickness.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Trial
- Mesopic Illumination in Natural Environments: Implications for Myopia Research.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Review
- Short-term exposure to cyan light attenuates myopigenic effects of hyperopic defocus on ocular biometry in humans.Scientific reports · 2026Article
- Interaction Between Near Work and Narrowband Light on Choroidal Thickness.Investigative ophthalmology & visual science · 2026Article
- IMI: The Role of Light in Refractive Development and Myopia: Evidence from Animal and Human Studies.Investigative ophthalmology & visual science · 2025Review
- Blue Light Defocus Induces A Positive Effect on Refractive Status and Ocular Health: A Randomized Crossover Trial.Global challenges (Hoboken, NJ) · 2025Article
- Influence of time-of-day and light wavelengths on ocular responses to defocus.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Effects of Blue Light Toward Emmetropization.Cureus · 2025Review
- Age-Related Regional Changes in Choroidal Vascularity in Healthy Emmetropic Eyes.Translational vision science & technology · 2025Article
- Chromatic imaging properties of myopia control spectacle lenses.Biomedical optics express · 2025Article
- Controlling ocular longitudinal chromatic aberration using a spatial light modulator.Biomedical optics express · 2025Article
- Peripheral Contrast Reduction Optically Induced by Scattering Lenses Thickens Peripheral Choroid.Translational vision science & technology · 2024Article
- Increase in choroidal thickness after blue light stimulation of the blind spot in young adults.Bioelectronic medicine · 2024Article
- Myopia Is an Ischemic Eye Condition: A Review from the Perspective of Choroidal Blood Flow.Journal of clinical medicine · 2024Review
- Influence of Aberration-Free, Narrowband Light on the Choroidal Thickness and Eye Length.Translational vision science & technology · 2024Article
- Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults.Investigative ophthalmology & visual science · 2024Article
- Adaptive Illuminance Effects on Retinal Morphology and Refraction: A Comprehensive Study of Night Myopia.Journal of clinical medicine · 2023Article
- The outdoor environment affects retinal and choroidal thickness.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023Article
- IMI-The Dynamic Choroid: New Insights, Challenges, and Potential Significance for Human Myopia.Investigative ophthalmology & visual science · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Purpose: To determine the effects of narrowband light exposure on choroidal thickness and the pupil response in humans. Methods: Twenty subjects, ages 21 to 43 years, underwent 1 hour of exposure to broadband, short wavelength "blue," or long wavelength "red" light, or darkness. Choroidal thickness, imaged with spectral domain optical coherence tomography, axial length, determined from biometry, and rod/cone- and intrinsically photosensitive retinal ganglion cell-driven pupil responses were measured before and after exposure. Pupil stimuli were six 1 second alternating red (651 nm) and blue (456 nm) stimuli, 60 seconds apart. Pupil metrics included maximum constriction and the 6 second post-illumination pupil response (PIPR). Results: Compared with before exposure, the choroid significantly thinned after broadband light, red light, and dark exposure (all P < 0.05), but not after blue light exposure (P = 0.39). The maximum constriction to 1 second red stimuli significantly decreased after all light exposures (all P < 0.001), but increased after dark exposure (P = 0.02), compared with before exposure. Maximum constriction and 6-second PIPR to 1 second blue stimuli significantly decreased after all light exposures compared with before exposure (all P < 0.005), with no change after dark exposure (P > 0.05). There were no differences in axial length change or 6-second PIPR to red stimuli between exposures. Conclusions: Narrowband blue and red light exposure induced differential changes in choroidal thickness. Maximum constriction, a function of rod/cone activity, and the intrinsically photosensitive retinal ganglion cell-mediated PIPR were attenuated after all light exposures. Findings demonstrate differing effects of short-term narrowband light and dark exposure on the choroid, rod/cone activity, and intrinsically photosensitive retinal ganglion cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.