ArticleCritical care explorations2020
Skeletal Muscle Composition Predicts Outcome in Critically Ill Patients.
Article in Critical care explorations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Effects of Incretin-Based Therapies, Diet and Exercise Interventions, and Bariatric Surgery on Fat-Free Mass in Adults With Overweight or Obesity: A Systematic Review and Meta-Analysis.Diabetes, obesity & metabolism · 2026Pooled it
- Exploring the association between computed tomography (CT)-derived skeletal muscle mass and short- and long-term mortality in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2025Pooled it
- Prevalence and mortality risk of low skeletal muscle mass in critically ill patients: an updated systematic review and meta-analysis.Frontiers in nutrition · 2023Pooled it
- Function Over Mass: A Meta-Analysis on the Importance of Skeletal Muscle Quality in COVID-19 Patients.Frontiers in nutrition · 2022Pooled it
- Prognostic value of sarcopenia markers in geriatric patients presenting to the emergency department: a prospective study.BMC emergency medicine · 2026Observational
- Ectopic Fat distribution and adverse muscle composition in South Asians: Findings from the UK biobank.American journal of preventive cardiology · 2025Article
- The flux of energy in critical illness and the obesity paradox.Physiological reviews · 2025Review
- Observational
- Skeletal muscle size and quality in healthy kidney donors, normal range and clinical associations.Scientific reports · 2024Article
- Abdominal Body Composition Reference Ranges and Association With Chronic Conditions in an Age- and Sex-Stratified Representative Sample of a Geographically Defined American Population.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Myosteatosis is associated with coronary artery calcification in patients with type 2 diabetes.World journal of diabetes · 2024Article
- A new bio imagery user-friendly tool for automatic morphometry measurement on muscle cell cultures and histological sections.Scientific reports · 2024Article
- Muscle Quality Index is inversely associated with psychosocial variables among Chilean adolescents.BMC public health · 2023Article
- Back Extensor Strength as a Potential Marker of Frailty Using Propensity Score Matching and Machine Learning.Journal of clinical medicine · 2023Article
- Respiratory Musculature Evaluated by Computed Tomography in the Setting of Prolonged Mechanical Ventilation.Respiratory care · 2023Article
- Radiological assessment of skeletal muscle index and myosteatosis and their impact postoperative outcomes after liver transplantation.Radiology and oncology · 2023Article
- The Presence of Myosteatosis Is Associated with Age, Severity of Liver Disease and Poor Outcome and May Represent a Prodromal Phase of Sarcopenia in Patients with Liver Cirrhosis.Journal of clinical medicine · 2023Article
- Adverse muscle composition is a significant risk factor for all-cause mortality in NAFLD.JHEP reports : innovation in hepatology · 2023Article
- [Routine computed tomography body composition analysis-experience in intensive care patients].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023Review
- Myosteatosis as an independent predictor of short-term mortality in successfully reperfused acute ischemic stroke.The neuroradiology journal · 2023Observational
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parameters of patients' body composition have been suggested as prognostic markers in several clinical conditions including cancer and liver transplantation, but only limited data on its value in critical illness exist to date. In this study, we aimed at evaluating a potential prognostic value of the skeletal muscle mass and skeletal muscle myosteatosis of critically ill patients at admission to the ICU.
designExploratory observational cohort study.
settingAn urban, academic medical institution. PATIENTS: One-hundred fifty-five patients treated for critical illness on a medical ICU.
interventionsNone. MEASUREMENTS AND MAIN
resultsWe used routine CT scans to assess the patients' individual body composition. The skeletal muscle index as a surrogate for sarcopenia was defined as the total skeletal muscle area at the level of the third lumbar vertebra on axial CT scan, normalized for the patient's height. Myosteatosis was evaluated by assessing the mean skeletal muscle attenuation measured in Hounsfield unit at the same sectional plane. The skeletal muscle index and mean skeletal muscle attenuation at admission to the ICU were significantly higher in patients with long-term survival (180-day or 1-year mortality), while both parameters were comparable between short-term survivors and nonsurvivors (ICU mortality or 30-d mortality). Patients with a skeletal muscle index or mean skeletal muscle attenuation below our established ideal cutoff values (74.95 mm
conclusionsOur data suggest that sarcopenia and myosteatosis represent important prognostic factors in critically ill patients that can be easily obtained from routine CT scans. Both parameters at admission to the ICU yield important information on the patients' long-term outcome and might be used for early clinical decision-making in these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.