Evidence map›Paper›PMID 32832672›Full record

ArticleScience advances2020

Peptidoglycan editing provides immunity to

Nguyen-Hung Le, Katharina Peters, Akbar Espaillat, Jessica R Sheldon, Joe Gray, Gisela Di Venanzio, Juvenal Lopez, Bardya Djahanschiri, Elizabeth A Mueller, Seth W Hennon and 6 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 61 citations in OpenAlex.

  1. Engineering the probioticSynthetic and systems biotechnology · 2026
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  9. The interplay betweenInfection and immunity · 2025
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  12. mBio · 2024
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  13. T6SS nuclease effectors inJournal of bacteriology · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Defense and anti-defense mechanisms of bacteria and bacteriophages.Journal of Zhejiang University. Science. B · 2024
    Article
  18. Chemical science · 2024
    Article
  19. Value of T6SS Core GeneIndian journal of microbiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

Nguyen-Hung LeDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-8659-6949
Katharina PetersCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, NE2 4AX Newcastle upon Tyne, UK.
Akbar EspaillatLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå University, 90187 Umeå, Sweden.
Jessica R SheldonDepartment of Pathology, Microbiology, and Immunology and Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0002-1413-9404
Joe GrayBiosciences Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-2338-0301
Gisela Di VenanzioDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-1969-3145
Juvenal LopezDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-3433-2412
Bardya DjahanschiriApplied Bioinformatics Group, Institute of Cell Biology and Neuroscience, Goethe University Frankfurt, Frankfurt am Main 60438, Germany.ORCID 0000-0002-6066-8315
Elizabeth A MuellerDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63105, USA.ORCID 0000-0001-5482-6551
Seth W HennonDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Petra Anne LevinDepartment of Biology, Washington University in St. Louis, St. Louis, MO 63105, USA.ORCID 0000-0003-2071-0547
Ingo EbersbergerApplied Bioinformatics Group, Institute of Cell Biology and Neuroscience, Goethe University Frankfurt, Frankfurt am Main 60438, Germany.ORCID 0000-0001-8187-9253
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology and Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0001-5094-8105
Felipe CavaLaboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, Umeå Centre for Microbial Research, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0001-5995-718X
Waldemar VollmerCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, NE2 4AX Newcastle upon Tyne, UK.
Mario F FeldmanDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-4497-0976
Washington University in St. Louis · USNewcastle University · GBGoethe University Frankfurt · DEUmeå University · SEVanderbilt University Medical Center · US

Funding

Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
HOMEOSTATIC CONTROL OF BACTERIAL GROWTH AND CELL DIVISIONR35GM127331 · NIGMS · WASHINGTON UNIVERSITY · PI Petra Anne Levin · 2018 to 2026
$4.3M
PEPTIDOGLYCAN MODIFICATION AS AN IMMUNITY MECHANISM AGAINST TYPE 6 SECRETION ATTACK IN ACINETOBACTERR21AI137188 · NIAID · WASHINGTON UNIVERSITY · PI FELDMAN, MARIO · 2018 to 2019
$419k
Medical Research Council MR/N002679/1NIAID NIH HHS R01 AI101171NIAID NIH HHS R21 AI137188NIGMS NIH HHS R35 GM127331Wellcome TrustWellcome Trust 101824/Z/13/Z
6 · The paper itself

Abstract

Peptidoglycan (PG) is essential in most bacteria. Thus, it is often targeted by various assaults, including interbacterial attacks via the type VI secretion system (T6SS). Here, we report that the Gram-negative bacterium

Indexed as

Acinetobacter baumanniiBiological WarfareAmino AcidsBacterial ProteinsHumansHydrogen PeroxidePeptidoglycanPhylogenyAmino AcidsBacterial ProteinsHydrogen PeroxidePeptidoglycan

Identifiers

PMID32832672
PMCPMC7439305
OpenAlexW3044915156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.