Evidence map›Paper›PMID 32832653›Full record

ArticleScience advances2020

Structure-specific DNA recombination sites: Design, validation, and machine learning-based refinement.

Aleksandra Nivina, Maj Svea Grieb, Céline Loot, David Bikard, Jean Cury, Laila Shehata, Juliana Bernardes, Didier Mazel

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Natural History of Integrons.Microorganisms · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Towards an engineering theory of evolution.Nature communications · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aleksandra NivinaUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.ORCID 0000-0002-1802-3724
Maj Svea GriebUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.
Céline LootUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.ORCID 0000-0003-3774-249X
David BikardUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.ORCID 0000-0002-5729-1211
Jean CuryUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.ORCID 0000-0002-6462-8783
Laila ShehataUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.ORCID 0000-0001-5037-9731
Juliana BernardesLaboratoire de Biologie Computationnelle et Quantitative, Sorbonne Universités, CNRS UMR 7238,75005 Paris, France.ORCID 0000-0003-1341-4256
Didier MazelUnité Plasticité du Génome Bactérien, Institut Pasteur, 75724 Paris, France.ORCID 0000-0001-6482-6002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recombination systems are widely used as bioengineering tools, but their sites have to be highly similar to a consensus sequence or to each other. To develop a recombination system free of these constraints, we turned toward

Identifiers

PMID32832653
PMCPMC7439510

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.