Evidence map›Paper›PMID 32832636›Full record

ArticleScience advances2020

Co-delivery of IKBKE siRNA and cabazitaxel by hybrid nanocomplex inhibits invasiveness and growth of triple-negative breast cancer.

Zhen Zhao, Yuanke Li, Hao Liu, Akshay Jain, Pratikkumar Vinodchandra Patel, Kun Cheng

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
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  9. Article
  10. Review
  11. Article
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  13. Review
  14. Topical Drug Delivery of Concentrated Cabazitaxel in an α-Tocopherol and DMSO Solution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  15. siRNA and targeted delivery systems in breast cancer therapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  16. Article
  17. Article
  18. Emerging Progress of RNA-Based Antitumor Therapeutics.International journal of biological sciences · 2023
    Review
  19. Polyphyllin I EffectsEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhen ZhaoDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.ORCID 0000-0001-8718-4778
Yuanke LiDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.ORCID 0000-0002-8304-8768
Hao LiuDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.
Akshay JainDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.
Pratikkumar Vinodchandra PatelDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.
Kun ChengDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108, USA.ORCID 0000-0001-9544-4680
University of Missouri–Kansas City · US

Funding

Targeted delivery of PCBP2 siRNA for treating alcoholic liver fibrosisR01AA021510 · NIAAA · UNIVERSITY OF MISSOURI KANSAS CITY · PI CHENG, KUN · 2012 to 2022
$3.8M
Development of a targeted delivery platform for checkpoint inhibitorsR01CA231099 · NCI · UNIVERSITY OF MISSOURI KANSAS CITY · PI CHENG, KUN · 2018 to 2022
$1.8M
Peptide-based conjugate for a water-insoluble drug treating advanced prostate cancerR01GM121798 · NIGMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI CHENG, KUN · 2017 to 2020
$1.2M
Age, gender and skeletal muscle microcirculationR21AG021510 · NIA · WEST VIRGINIA UNIVERSITY · PI HAMMER, LEAH W · 2003 to 2004
$441k
NCI NIH HHS R01 CA231099NIAAA NIH HHS R01 AA021510NIA NIH HHS R21 AG021510NIGMS NIH HHS R01 GM121798
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Triple Negative Breast NeoplasmsAnimalsCell Line, TumorHumansI-kappa B KinaseMiceRNA, Small InterferingTaxoidscabazitaxelI-kappa B KinaseIKBKE protein, humanRNA, Small InterferingTaxoids

Identifiers

PMID32832636
PMCPMC7439402
OpenAlexW3043758280

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.