ArticleACS biomaterials science & engineering2017
Orthopedic Interface Repair Strategies Based on Native Structural and Mechanical Features of the Multiscale Enthesis.
Article in ACS biomaterials science & engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Histologic outcomes of rotator cuff patch augmentation: a literature review.JSES reviews, reports, and techniques · 2026Review
- Bone patellar tendon bone graft for ulnar collateral ligament reconstruction: a biomechanical study.JSES reviews, reports, and techniques · 2025Article
- An ultrastructure analysis of the developing human anterior cruciate ligament tibial enthesis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Gradient scaffolds in bone-soft tissue interface engineering: Structural characteristics, fabrication techniques, and emerging trends.Journal of orthopaedic translation · 2025Review
- 3D-Printed Poly(3-hydroxybutyrate-Biomacromolecules · 2023Article
- Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death.Developmental dynamics : an official publication of the American Association of Anatomists · 2023Article
- Anatomical Tissue Engineering of the Anterior Cruciate Ligament Entheses.International journal of molecular sciences · 2023Review
- Linguistic Analysis Identifies Emergent Biomaterial Fabrication Trends for Orthopaedic Applications.Advanced healthcare materials · 2023Review
- 3D cell-printing of gradient multi-tissue interfaces for rotator cuff regeneration.Bioactive materials · 2023Article
- Joining soft tissues to bone: Insights from modeling and simulations.Bone reports · 2021Review
- Integrated Multiscale Biomaterials Experiment and Modeling.ACS biomaterials science & engineering · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The enthesis is an organ that connects a soft, aligned tissue (tendon/ligament) to a hard, amorphous tissue (bone) via a fibrocartilage interface. Mechanically, the enthesis sustains a dynamic loading environment that includes tensile, compressive, and shear forces. The structural components of the enthesis act to minimize stress concentrations and control stretch at the interface. Current surgical repair of the enthesis, such as in rotator cuff repair and anterior cruciate ligament reconstruction, aim to bridge the gap between the injured ends via reattachment of soft-to-hard tissues or graft replacement. In this review, we discuss the multiscale, morphological, and mechanical characteristics of the fibrocartilage attachment. Additionally, we review historical and recent clinical approaches to treating enthesis injury. Lastly, we explore new technological advancements in tissue-engineered biomaterials that have shown promise in preclinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.