Evidence map›Paper›PMID 32832544›Full record

ArticleBioMed research international2020

Study of Osteoarthritis-Related Hub Genes Based on Bioinformatics Analysis.

Zhengqing Zhu, Lei Zhong, Ronghang Li, Yuzhe Liu, Xiangrun Chen, Zhaoyan Li, Lanfeng Huang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Transcriptomics in the Study of Bone and Cartilage.Current osteoporosis reports · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Identification ofAnnals of translational medicine · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhengqing ZhuDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-0109-1771
Lei ZhongDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.
Ronghang LiDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yuzhe LiuDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xiangrun ChenDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.
Zhaoyan LiDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-7324-9507
Lanfeng HuangDepartments of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0002-4273-506X
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a common cause of morbidity and disability worldwide. However, the pathogenesis of OA is unclear. Therefore, this study was conducted to characterize the pathogenesis and implicated genes of OA. The gene expression profiles of GSE82107 and GSE55235 were downloaded from the Gene Expression Omnibus database. Altogether, 173 differentially expressed genes including 68 upregulated genes and 105 downregulated genes in patients with OA were selected based on the criteria of ∣log fold-change | >1 and an adjusted

Indexed as

Computational BiologyDatabases, Nucleic AcidGene Expression RegulationGene Regulatory NetworksOsteoarthritisProtein Interaction MapsBiomarkersFemaleGene Expression ProfilingHumansMaleBiomarkers

Identifiers

PMID32832544
PMCPMC7428874
OpenAlexW3047478742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.