ArticleHepatobiliary surgery and nutrition2020
New-onset diabetes after adult liver transplantation in the Korean Organ Transplantation Registry (KOTRY) study.
Article in Hepatobiliary surgery and nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 16 citations in OpenAlex.
- Living with a transplanted liver is associated with diabetes.Scientific reports · 2026Article
- Risk of Incident Post-Transplantation Diabetes Mellitus After Solid Organ Transplantation in Taiwan: A Population-Based Cohort Study.Healthcare (Basel, Switzerland) · 2025Article
- Safety and efficacy of early corticosteroid withdrawal in liver transplant recipients: A randomized controlled trial.Annals of hepato-biliary-pancreatic surgery · 2024Article
- Clinical characteristics of new-onset diabetes after liver transplantation and outcomes.Annals of gastroenterological surgery · 2024Article
- Non-Renal Risk Factors for Chronic Kidney Disease in Liver Recipients with Functionally Intact Kidneys at 1 Month.Journal of clinical medicine · 2022Article
- New-onset diabetes after transplantation: remaining issues to be discussed.Hepatobiliary surgery and nutrition · 2021Article
- The need for deepened molecular mechanism exploration in new onset diabetes after transplantation (NODAT).Hepatobiliary surgery and nutrition · 2021Article
- New onset diabetes mellitus after liver transplantation.Hepatobiliary surgery and nutrition · 2021Article
- Outcomes after liver transplantation in Korea: Incidence and risk factors from Korean transplantation registry.Clinical and molecular hepatology · 2021Article
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18 authors at 9 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundNew-onset diabetes after transplantation (NODAT) is a serious complication following liver transplantation (LT). The present study aimed to investigate the incidence of and risk factors for NODAT using the Korean Organ Transplantation Registry (KOTRY) database.
methodsPatients with history of pediatric transplantation (age ≤18 years), re-transplantation, multi-organ transplantation, or pre-existing diabetes mellitus were excluded. A total of 1,919 non-diabetic adult patients who underwent a primary LT between May 2014 and December 2017 were included. Risk factors were identified using Cox regression analysis.
resultsNODAT occurred in 19.7% (n=377) of adult liver transplant recipients. Multivariate analysis showed steroid use, increased age, and high body mass index (BMI) in recipients, and implantation of a left-side liver graft was closely associated with NODAT in adult LT. In living donor liver transplant (LDLT) patients (n=1,473), open donor hepatectomy in the living donors, steroid use, small for size liver graft (graft to recipient weight ratio ≤0.8), increased age, and high BMI in the recipient were predictive factors for NODAT. The use of antimetabolite and basiliximab induction reduced the incidence of NODAT in adult LT and in adult LDLT.
conclusionsBasiliximab induction, early steroid withdrawal, and antimetabolite therapy may prevent NODAT after adult LT. High BMI or advanced age in liver recipients, open donor hepatectomy in living donors, and small size liver graft can predict the occurrence of NODAT after adult LT or LDLT.
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