ReviewIndian dermatology online journal
What is New in the Pathogenesis and Management of Erythema Nodosum Leprosum.
Review in Indian dermatology online journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Neutrophil-to-lymphocyte ratio as a biomarker in erythema nodosum leprosum: A systematic review and meta-analysis.New microbes and new infections · 2026Review
- "Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches-A Narrative Review".Health science reports · 2026Article
- Delayed diagnosis and poor treatment compliance remain key challenges in leprosy control: a case of lepromatous leprosy with type 2 reaction.BMC infectious diseases · 2026Article
- Article
- Article
- Type 2 Lepra Reaction with Borderline Lepromatous Leprosy.Dermatology practical & conceptual · 2025Article
- Revealing Erythema Nodosum Leprosum in a Leprosy Patient: A Case of Treatment Noncompliance.Case reports in infectious diseases · 2025Article
- Bullous Type 2 Lepra Reaction: A Rare and Significant Case Report.Clinical case reports · 2025Article
- Article
- Review
- Erythema nodosum leprosum as the initial presentation of lepromatous leprosy.JAAD case reports · 2024Article
- Case Report: Nonalcoholic Hepatic Steatosis Associated with Type-2 Leprosy Reaction.The American journal of tropical medicine and hygiene · 2024Article
- Split Dose of Prednisolone in the Treatment for Erythema Nodosum Leprosum: A Case Series.Cureus · 2024Article
- Article
- Steroid Premedication Might Protect From Postoperative Erythema Nodosum Leprosum in Leprosy: A Case Report.Cureus · 2024Article
- Erythema nodosum leprosum necroticans: a case report of an atypical severe type 2 leprosy reaction and literature review.Le infezioni in medicina · 2024Article
- Leprosy Reactions: Experience in the Puerto Rico Hansen's Disease Population.Puerto Rico health sciences journal · 2023Article
- Systemic manifestation of necrotic erythema nodosum leprosum: A case report of a fatal leprosy.Narra J · 2023Article
- Case Report: Necrotizing Erythema Nodosum as a Manifestation of Lepromatous Leprosy Relapse 50 Years after the Initial Infection.The American journal of tropical medicine and hygiene · 2023Article
- Pathogenicity and virulence ofVirulence · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erythema nodosum leprosum (ENL) is a manifestation of type II lepra reaction, seen in lepromatous or borderline lepromatous leprosy. Although it is a common reaction encountered in clinical practice, there are an increasingly large number of newer updates in the pathophysiology and management of this condition. The treatment options have expanded far beyond just thalidomide and steroids and now extends to TNF-α inhibitors, thalidomide analogs, tenidap, cyclosporine A, plasma exchange, and even IVIG amongst others. These updates and the current knowledge of ENL are summarized in this review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.