Evidence map›Paper›PMID 32832273›Full record

ArticlePeerJ2020

Proteins from

Boon Hong Kong, Kean Hooi Teoh, Nget Hong Tan, Chon Seng Tan, Szu Ting Ng, Shin Yee Fung

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Comparative Cytotoxicity Evaluation of Heat-AssistedFood technology and biotechnology · 2024
    Article
  5. Review
  6. Antioxidant and Cytotoxic Effects and Identification ofFood technology and biotechnology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Boon Hong KongMedicinal Mushroom Research Group, Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Wilayah Persekutuan, Malaysia.
Kean Hooi TeohDepartment of Pathology, University of Malaya, Kuala Lumpur, Malaysia.
Nget Hong TanMedicinal Mushroom Research Group, Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Wilayah Persekutuan, Malaysia.
Chon Seng TanLigno Research Initiative, Ligno Biotech Sdn Bhd, Balakong Jaya, Malaysia.
Szu Ting NgLigno Research Initiative, Ligno Biotech Sdn Bhd, Balakong Jaya, Malaysia.
Shin Yee FungMedicinal Mushroom Research Group, Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Wilayah Persekutuan, Malaysia.
University of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe cytotoxicity of the Ligno TG-K against human breast (MCF7), prostate (PC3) and lung (A549) adenocarcinoma cell lines was evaluated using MTT cytotoxicity assay. The cytotoxic mechanisms of the active high molecular weight proteins (HMWp) fraction were investigated through detection of caspases activity and apoptotic-related proteins expression by Western blotting. The in vivo antitumor activity of the isolated HMWp was examined using MCF7 mouse xenograft model. Shotgun LC-MS/MS analysis was performed to identify the proteins in the HMWp. RESULTS AND DISCUSSION: Cold water extract of the sclerotia inhibited proliferation of MCF7, A549 and PC3 cells with IC

conclusionThe findings from this study provided scientific evidences to support the traditional use of the

Indexed as

ApoptosisCytotoxicityIn vivo antitumorLignosus tigris (Polyporaceae)Proteins

Identifiers

PMID32832273
PMCPMC7413093
OpenAlexW3047558857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.