ArticleTranslational vision science & technology2020
Limbal Metabolic Support Reduces Peripheral Corneal Edema with Contact-Lens Wear.
Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- A new three-dimensional model to describe human corneal oxygenation during contact lenses wear.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Longitudinal evaluation of corneal stability and tear film changes in first-time soft-contact lens wearers.Arquivos brasileiros de oftalmologia · 2025Article
- Commentary - Scleral lenses: The leading edge.Indian journal of ophthalmology · 2023Article
- A three-dimensional model to describe complete human corneal oxygenation during contact lens wear.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Therapeutic Hyper-CL soft contact lens in Sjögren's syndrome.American journal of ophthalmology case reports · 2022Article
- Therapeutic HL-Contact Lens versus Standard Bandage Contact Lens for Corneal Edema: A Prospective, Multicenter, Randomized, Crossover Study.Journal of ophthalmology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To assess the influence of limbal metabolic support on corneal edema during scleral-lens (SL) and soft-contact-lens (SCL) wear for healthy lens wearers. Methods: A two-dimensional (2D) model of the cornea and sclera was designed on Comsol Multiphysics 5.4 along with SL and SCL architectures to mimic lens-wear induced hypoxia. The cornea is suffused with oxygen and metabolites from the limbus and aqueous humor. Air oxygen is supplied from and carbon dioxide is expelled to the atmosphere. Lens-oxygen permeability ( Results: The metabolic model assesses central-to-peripheral corneal swelling with different types of lenses, and oxygen Conclusions: The metabolic model accurately predicts central-to-peripheral corneal edema with various contact-lens designs, post-lens tear-film thicknesses, and lens oxygen Translational Relevance: By utilizing metabolic kinetics, we provide a 2D computational tool to predict oxygenation safety across the entire cornea with various types and designs of contact lenses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.