Evidence map›Paper›PMID 32832239›Full record

ArticleTranslational vision science & technology2020

Repeatability and Reproducibility of Total Retinal Blood Flow Measurements Using Bi-Directional Doppler OCT.

Stephan Szegedi, Nikolaus Hommer, Martin Kallab, Stefan Puchner, Doreen Schmidl, René M Werkmeister, Gerhard Garhöfer, Leopold Schmetterer

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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  6. Retinal Oxygen Extraction in Patients with Primary Open-Angle Glaucoma.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Stephan SzegediDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
Nikolaus HommerDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
Martin KallabDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
Stefan PuchnerDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
Doreen SchmidlDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
René M WerkmeisterCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Austria.
Gerhard GarhöferDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
Leopold SchmettererDepartment of Clinical Pharmacology, Medical University of Vienna, Austria.
Medical University of Vienna · ATNanyang Technological University · SG

Funding

Austrian Science Fund FWF KLI 529
6 · The paper itself

Abstract

Purpose: To investigate the repeatability and reproducibility of total retinal blood flow measurements using a custom-built dual-beam bidirectional Doppler optical coherence tomography (OCT) system in healthy subjects. Methods: Repeatability and reproducibility were analyzed in 10 and 34 healthy subjects, respectively. For repeatability, measurements were taken twice within 30 minutes, for reproducibility, twice within two to five weeks. Two analysis approaches were compared for calculation of absolute blood velocities: a previously published approach resulting in values for total arterial (Q Results: For Q Conclusions: Measurement of total retinal blood flow using dual-beam Doppler OCT shows excellent reproducibility, which can further be improved by using a novel algorithm for calculating blood velocities in retinal vessels. Translational Relevance: Our data indicate that dual-beam Doppler OCT can be used for longitudinal studies. Hence, quantitative retinal blood flow may be established as a biomarker for progression vascular eye diseases.

Indexed as

Retinal VesselsTomography, Optical CoherenceFourier AnalysisHumansRegional Blood FlowReproducibility of Resultshealthy subjectsrepeatabilityretinal blood flow

Identifiers

PMID32832239
PMCPMC7414639
OpenAlexW3037204814

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.