Evidence map›Paper›PMID 32832146›Full record

ArticleCardiology research and practice2020

Association of c.56C > G (rs3135506) Apolipoprotein A5 Gene Polymorphism with Coronary Artery Disease in Moroccan Subjects: A Case-Control Study and an Updated Meta-Analysis.

Imane Morjane, Hicham Charoute, Sanaa Ouatou, Lamiae Elkhattabi, Houda Benrahma, Rachid Saile, Hassan Rouba, Abdelhamid Barakat

Open access · goldAbstract read
In one paragraph

Article in Cardiology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Imane MorjaneLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.ORCID https://orcid.org/0000-0001-9123-7289
Hicham CharouteLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.
Sanaa OuatouLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.
Lamiae ElkhattabiLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.
Houda BenrahmaLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.
Rachid SaileLaboratory of Biology and Health, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca, Morocco.ORCID https://orcid.org/0000-0002-7411-0523
Hassan RoubaLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.
Abdelhamid BarakatLaboratory of Genomics and Human Genetics, Institut Pasteur Du Maroc, Casablanca, Morocco.ORCID https://orcid.org/0000-0002-6239-0281
Institut Pasteur du Maroc · MAUniversité Mohammed VI des Sciences et de la Santé · MAUniversity of Hassan II Casablanca · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCoronary artery diseases (CAD) are clinical cardiovascular events associated with dyslipidemia in common. The interaction between environmental and genetic factors can be responsible for CAD. The present paper aimed to examine the association between c.56C > G (rs3135506) APOA5 gene polymorphism and CAD in Moroccan individuals and to perform an association update meta-analysis. MATERIALS AND

methodsThe c.56C > G variant was genotyped in 122 patients with CAD and 134 unrelated controls. Genetic association analysis and comparison of biochemical parameters were performed using

resultsThe case-control study data showed that the c.56C > G polymorphism was associated with CAD susceptibility under codominant (

conclusionOur case-control study revealed a significant association between c.56C > G polymorphism and CAD in the Moroccan population. In addition, meta-analysis data supported the implication of this polymorphism in CAD susceptibility.

Identifiers

PMID32832146
PMCPMC7424381
OpenAlexW3047168153

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.