Evidence map›Paper›PMID 32832042›Full record

ArticleInternational journal of organ transplantation medicine2020

E M Dobrindt, M Biebl, S Rademacher, C Denecke, A Andreou, J Raakow, D Kröll, R Öllinger, J Pratschke, S S Chopra

Open access · greenAbstract read
In one paragraph

Article in International journal of organ transplantation medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Incidence, screening, and management ofWorld journal of transplantation · 2025
    Review
  2. Total Robot-Assisted Minimally Invasive Esophagectomy for De Novo Esophageal Cancer after Liver Transplantation: The Potential of Robotic Surgery in a Complex Posttransplant Case.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

E M DobrindtDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
M BieblDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
S RademacherDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, Universitätsklinikum Leipzig, Leipzig, Germany.
C DeneckeDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
A AndreouDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
J RaakowDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
D KröllDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
R ÖllingerDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
J PratschkeDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
S S ChopraDepartment of Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunosuppression is essential after liver transplantation (LT). It, however, increases the risk for cancer.

objectiveTo evaluate the prevalence and outcome of upper gastrointestinal (GI) tract cancer in LT patients and assess the perioperative risk of surgery for the upper GI malignancies post-LT.

methods2855 patients underwent LT at our clinic from 1988 to 2018. 20 patients developed upper GI cancer. Data were retrospectively extracted from our database. Analysis included patients' specific data, tumor histopathology and stage, the treatment given and survival.

results23 patients developed upper GI malignancies (2 gastric and 18 esophageal cancers; 3 excluded), translating to a incidence of 26.4 per 100,000 population per year. All patients were male. 80% showed alcohol-induced cirrhosis before LT. Most of the tumors were diagnosed at a stage ≥III. 70% underwent surgery and 78.6% developed postoperative complications. One-year-survival was 50%. Total survival rate was 28.6% with a median follow-up of 10 months (range: 0-184).

conclusionUpper GI malignancies are more common after LT compared to the general population. Men after LT, due to alcohol-induced liver cirrhosis, are at a higher risk. Upper GI surgery after LT can be safe, but the severe risk for complications and a poor survival require strict indications.

Indexed as

Esophageal cancerEsophagectomyImmunosuppressionSquamous cell cancer

Identifiers

PMID32832042
PMCPMC7430062
OpenAlexW3041714031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.