Evidence map›Paper›PMID 32831998›Full record

ArticleOxidative medicine and cellular longevity2020

Short-Chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43-Mediated Inhibition of Oxidative Stress and NF-

Wei Huang, Yi Man, Chenlin Gao, Luping Zhou, Junling Gu, Huiwen Xu, Qin Wan, Yang Long, Li Chai, Youhua Xu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 4 pooled it
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 4 syntheses or guidelines pooled it, 186 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The roles of free-fatty acid receptors in the pathophysiology of renal disorders.The Journal of pharmacology and experimental therapeutics · 2026
    Review
  6. Observational
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Structural-activity relationship ofFrontiers in immunology · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Wei HuangDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0002-9744-8762
Yi ManAffiliated Hospital of Southwest Medical University, Luzhou, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0003-3059-4666
Chenlin GaoDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0003-2464-9325
Luping ZhouDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0003-1065-6604
Junling GuDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0002-8451-7992
Huiwen XuDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0001-6487-9702
Qin WanDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0003-1363-3010
Yang LongDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.
Li ChaiDepartment of Pathology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0001-9218-2283
Youhua XuFaculty of Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macau, China.ORCID https://orcid.org/0000-0002-3258-013X
Yong XuDepartment of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China 646000.ORCID https://orcid.org/0000-0002-9534-6252
Affiliated Hospital of Southwest Medical University · CNMacau University of Science and Technology · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic nephropathy (DN) is a chronic low-grade inflammatory disease. Oxidative stress and nuclear factor kappa B (NF-

Indexed as

AnimalsDiabetic NephropathiesDisease Models, AnimalFatty Acids, VolatileHumansMaleMiceNF-kappa BOxidative StressReceptors, G-Protein-CoupledTransfectionFatty Acids, VolatileFfar2 protein, mouseNF-kappa BReceptors, G-Protein-Coupled

Identifiers

PMID32831998
PMCPMC7422068
OpenAlexW3046795374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.