ArticleUltrasound (Leeds, England)2020
Added value of strain elastography in the characterisation of breast lesions: A prospective study.
Article in Ultrasound (Leeds, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The value of multi-parametric ultrasonography nomogram in predicting nipple-areolar complex involvement in breast cancer.Quantitative imaging in medicine and surgery · 2026Article
- Multi-center strain elastography radiomics for breast cancer diagnosis: integrating intratumoral and peritumoral regions.Discover oncology · 2025Article
- Development and Validation of a Nomogram for Predicting Breast Malignancy in Male Patients Based on Clinical and Ultrasound Features.Current radiopharmaceuticals · 2024Article
- Compression optical coherence elastography versus strain ultrasound elastography for breast cancer detection and differentiation: pilot study.Biomedical optics express · 2022Article
- Clinical use and adjustment of ultrasound elastography for breast lesions followed WFUMB guidelines and recommendations in the real world.Frontiers in oncology · 2022Article
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Authors and funding
4 authors.
Funding
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Abstract
backgroundElastography is a new promising ultrasonographic technique which is used to differentiate benign and malignant breast lesions based on the stiffness of the lesion. PURPOSE: To determine the role of strain elastography in characterisation of breast lesions and to compare the diagnostic performances of strain elastography and conventional ultrasound (US).
methodsIn total, 113 breast lesions in 100 women were prospectively evaluated by US and strain elastography followed by the histopathological examination. Elastography score based on the Tsukuba colour scale and strain ratio were determined for each lesion. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value were calculated for each modality and the diagnostic performances were compared. The best cut-off point was calculated for each of the elastography parameters using the receiver operator curve analysis.
resultsOut of the 113 lesions, 40 were malignant (35.4%) and 73 were benign (64.6%). The area under the curve for elastography score showed significant difference with that of US: 0.98 versus 0.90 (Difference = 0.08,
conclusionStrain elastography is a useful adjunct to conventional ultrasonography. The combined use of strain elastography and ultrasound improves the characterisation of breast lesions and helps in down-staging of assigned BI-RADS category, thereby avoiding unnecessary biopsies. ES is the most useful elastography parameter to differentiate between benign and malignant breast lesions.
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