Evidence map›Paper›PMID 32831884›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Study on the Multitarget Mechanism of Sanmiao Pill on Gouty Arthritis Based on Network Pharmacology.

Huiqin Qian, Qianqian Jin, Yichen Liu, Ning Wang, Yuru Chu, Bingbing Liu, Yan Liu, Wanli Jiang, Yong Song

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Huiqin QianCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.ORCID https://orcid.org/0000-0001-5298-4505
Qianqian JinOtolaryngological Department, Puyang Oilfield General Hospital, Puyang 457000, China.
Yichen LiuCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Ning WangCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Yuru ChuCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Bingbing LiuCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Yan LiuCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Wanli JiangCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Yong SongCollege of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang 453000, China.
Xinxiang Medical University · CNDaqing Oilfield General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sanmiao pill (SMP), a Chinese traditional formula, had been used to treat gouty arthritis (GA). However, the active compounds and underlying mechanism remained unclear. Hence, network pharmacology and molecular docking were utilized to explore bioactive compounds and potential mechanism of action of SMP in treating GA. In the study, the compounds of SMP, corresponding targets, and GA-related targets were mined from various pharmacological databases. Then, herb-compound-target, compound-target, PPI, and target-pathway networks were constructed. Ultimately, molecular docking was carried out to verify the predicted results. The results indicated that 47 active compounds, 338 targets, and 144 disease targets were collected. Network analysis implied that

Identifiers

PMID32831884
PMCPMC7424379
OpenAlexW3047568879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.