Evidence map›Paper›PMID 32831873›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Gan-Qing-Ning Formula Inhibits the Growth of Hepatocellular Carcinoma by Promoting Apoptosis and Inhibiting Angiogenesis in H

Fan-Yan Zeng, Kai-Li Zhao, Le-Zhen Lin, Ying Deng, Si Qin, Jin-Rong Ye, Zeng-Qiong Huang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fan-Yan ZengAffiliated Tumor Hospital, Guangxi Medical University, Nanning, Guangxi 530021, China.
Kai-Li ZhaoCollege of Pharmacy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Le-Zhen LinCollege of Pharmacy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Ying DengCollege of Pharmacy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Si QinCollege of Pharmacy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Jin-Rong YeCollege of Pharmacy, Guangxi Medical University, Nanning, Guangxi 530021, China.
Zeng-Qiong HuangCollege of Pharmacy, Guangxi Medical University, Nanning, Guangxi 530021, China.ORCID https://orcid.org/0000-0002-1968-8744
Guangxi Medical University · CNTumor Hospital of Guangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGang-Qing-Ning (GQN) is a traditional Chinese medicine formula that has been used in the treatment of hepatocellular carcinoma (HCC) in the folk population for decades. However, scientific validation is still necessary to lend credibility to the traditional use of GQN against HCC. This study investigates the antitumor effect of GQN on H

methodsFifty H

resultsThe tumor inhibitory rates of high, medium, and low dosages of GQN groups were 47.39%, 38.26%, and 22.17%, respectively. The high dosage of the GQN group significantly increased the protein and mRNA expression levels of Bax, Cyt-C, and cleaved Caspase 3 (or Caspase 3) (

conclusionsThe high dosage of GQN can significantly inhibit the tumor growth in H

Identifiers

PMID32831873
PMCPMC7428871
OpenAlexW3047979525

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.