ArticleEvidence-based complementary and alternative medicine : eCAM2020
Acute Oral Toxicity and Anti-inflammatory and Analgesic Effects of Aqueous and Methanolic Stem Bark Extracts of
Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Ethnomedicinal Practices of the Fabaceae Family in Tanzania: A Systematic Review.TheScientificWorldJournal · 2026Pooled it
- Bridging in vitro bioactivities and in silico insights of Rubia cordifolia L. (Rubiaceae) leaf extracts for therapeutic applications.Scientific reports · 2026Article
- Article
- Ethnopharmacological considerations of plants traditionally used by local communities to manage maternal conditions in Tanzania: a scoping review.Frontiers in pharmacology · 2025Review
- Article
- Methanol Extract ofMolecules (Basel, Switzerland) · 2024Article
- Ionomic analysis, polyphenols characterization, analgesic, antiinflammatory and antioxidant capacities of Cistus laurifolius leaves: in vitro, in vivo, and in silico investigations.Scientific reports · 2023Article
- Effects of Ottonia anisum plant extract on local anesthetic, analgesic, anti-inflammatory and HCl‑induced acute lung injury activities: a study in animal models.Bioresources and bioprocessing · 2023Article
- Cytotoxicity, acute and sub-chronic toxicities of the leaves of Bauhinia thonningii (Schumach.) Milne-Redh. (Caesalpiniaceae).BMC complementary medicine and therapies · 2023Article
- Medicinal Uses of the Fabaceae Family in Zimbabwe: A Review.Plants (Basel, Switzerland) · 2023Review
- Analgesic and Anti-Inflammatory Activities of 80% Methanol Extract and Solvent Fractions ofJournal of experimental pharmacology · 2023Article
- Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19.Physics and chemistry of the earth (2002) · 2022Article
- A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Ethnomedicinal Information on Plants Used for the Treatment of Bone Fractures, Wounds, and Sprains in the Northern Region of the Republic of Benin.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Subacute Toxicity Effects of the Aqueous Shoot Extract ofJournal of toxicology · 2022Article
- Efficiency of Multiple Extraction Solvents on Antioxidant, Cytotoxic, and Phytotoxic Potential ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Article
- Acute Toxicity, Phytochemical Screening, Analgesic, and Anti-Inflammatory Activities of Aqueous and Methanol Root Extracts ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Ethnobotanical Documentation, Phytochemical Screening, and Cytotoxicity Evaluation of Medicinal Plants Used to Manage Snakebite Envenomation in Mwingi West Subcounty, Kenya.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Evaluation of the Antimicrobial Effect of the Extracts of the Pods ofAdvances in pharmacological and pharmaceutical sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation and pain are devastating conditions characterizing many diseases. Their manifestation ranges from mild body discomfort, to a debilitating experience, which may culminate in organ failure or death. In conventional medicine, corticosteroids, nonsteroidal anti-inflammatory drugs, opioids, and adjuvants are utilized to manage symptoms related to pain and inflammation. Despite their reported successes, these agents are only palliative, debatably inaccessible, unaffordable, and cause many undesirable side effects. As a result, the search for alternative and complementary therapies is warranted. Medicinal plants have been intensively utilized by humans for a long time to treat various ailments. In spite of their reported efficacies, empirical scientific data supporting their healing claims is scanty.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.