Evidence map›Paper›PMID 32831625›Full record

ArticleChemical engineering journal (Lausanne, Switzerland : 1996)2019

Microfluidics-enabled rational design of ZnO micro-/nanoparticles with enhanced photocatalysis, cytotoxicity, and piezoelectric properties.

Nanjing Hao, Zhe Xu, Yuan Nie, Congran Jin, Andrew B Closson, Michael Zhang, John X J Zhang

Abstract read
In one paragraph

Article in Chemical engineering journal (Lausanne, Switzerland : 1996), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Traditional vs. Microfluidic Synthesis of ZnO Nanoparticles.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Microfluidic Synthesis of -NHNanomaterials (Basel, Switzerland) · 2022
    Article
  8. Review
  9. Mild Microfluidic Approaches to Oxide Nanoparticles Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Acoustofluidics-Assisted Fluorescence-SERS Bimodal Biosensors.Small (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nanjing HaoThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.
Zhe XuThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.
Yuan NieThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.
Congran JinThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.
Andrew B ClossonThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.
Michael ZhangThe Lawrenceville School, 2500 Main St, Lawrenceville, New Jersey 08648, United States.
John X J ZhangThayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, United States.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Implantable Cardiac Power Generation Using Flexible 3D Porous Thin FilmsR01HL137157 · NHLBI · DARTMOUTH COLLEGE · PI ZHANG, XIAOJING · 2016 to 2020
$2.2M
NCI NIH HHS P30 CA023108NHLBI NIH HHS R01 HL137157
6 · The paper itself

Abstract

Microfluidics-based reactors enables the controllable synthesis of micro-/nanostructures for a broad spectrum of applications from materials science, bioengineering to medicine. In this study, we first develop a facile and straightforward flow synthesis strategy to control zinc oxide (ZnO) of different shapes (sphere, ellipsoid, short rod, long rod, cube, urchin, and platelet) on a few seconds time scale, based on the 1.5-run spiral-shaped microfluidic reactor with a relative short microchannel length of ca. 92 mm. The formation of ZnO is realized simply by mixing reactants through two inlet flows, one containing zinc nitrate and the other sodium hydroxide. The structures of ZnO are tuned by choosing appropriate flow rates and reactant concentrations of two inlet fluids. The formation mechanism behind microfluidics is proposed. The photocatalysis, cytotoxicity, and piezoelectric capabilities of as-synthesized ZnO from microreactors are further examined, and the structure-dependent efficacy is observed, where higher surface area ZnO structures generally behave better performance. These results bring new insights not only in the rational design of functional micro-/nanoparticles from microfluidics, but also for deeper understanding of the structure-efficacy relationship when translating micro-/nanomaterials into practical applications.

Indexed as

CytotoxicityMicrofluidicsPhotocatalysisPiezoelectricZinc oxide

Identifiers

PMID32831625
PMCPMC7441810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.