Evidence map›Paper›PMID 32831419›Full record

ArticleComputer methods in applied mechanics and engineering2019

Immersogeometric fluid-structure interaction modeling and simulation of transcatheter aortic valve replacement.

Michael C H Wu, Heather M Muchowski, Emily L Johnson, Manoj R Rajanna, Ming-Chen Hsu

Open access · greenAbstract read
In one paragraph

Article in Computer methods in applied mechanics and engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 72 citations in OpenAlex.

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  19. Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves.Computer methods in applied mechanics and engineering · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael C H WuDepartment of Mechanical Engineering, Iowa State University, 2043 Black Engineering, Ames, Iowa 50011, USA.
Heather M MuchowskiDepartment of Mechanical Engineering, Iowa State University, 2043 Black Engineering, Ames, Iowa 50011, USA.
Emily L JohnsonDepartment of Mechanical Engineering, Iowa State University, 2043 Black Engineering, Ames, Iowa 50011, USA.
Manoj R RajannaDepartment of Mechanical Engineering, Iowa State University, 2043 Black Engineering, Ames, Iowa 50011, USA.
Ming-Chen HsuDepartment of Mechanical Engineering, Iowa State University, 2043 Black Engineering, Ames, Iowa 50011, USA.
Iowa State University · US

Funding

Echocardiography to Predict Recurrent IMR After Surgical Mitral Valve ReplacementR01HL103723 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GORMAN, ROBERT C, HUNG, JUDY W · 2011 to 2020
$5.3M
Biomechanical indicators of bicuspid aortic valve dysfunctionR01HL142504 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI GORMAN, ROBERT C, HSU, MING-CHEN · 2018 to 2021
$2.9M
Novel Simulation Technologies for BHV Long-Term DurabilityR01HL129077 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI HUGHES, THOMAS J., MANNING, KEEFE B · 2016 to 2019
$2.1M
NHLBI NIH HHS R01 HL103723NHLBI NIH HHS R01 HL129077NHLBI NIH HHS R01 HL142504
6 · The paper itself

Abstract

The transcatheter aortic valve replacement (TAVR) has emerged as a minimally invasive alternative to surgical treatments of valvular heart disease. TAVR offers many advantages, however, the safe anchoring of the transcatheter heart valve (THV) in the patients anatomy is key to a successful procedure. In this paper, we develop and apply a novel immersogeometric fluid-structure interaction (FSI) framework for the modeling and simulation of the TAVR procedure to study the anchoring ability of the THV. To account for physiological realism, methods are proposed to model and couple the main components of the system, including the arterial wall, blood flow, valve leaflets, skirt, and frame. The THV is first crimped and deployed into an idealized ascending aorta. During the FSI simulation, the radial outward force and friction force between the aortic wall and the THV frame are examined over the entire cardiac cycle. The ratio between these two forces is computed and compared with the experimentally estimated coefficient of friction to study the likelihood of valve migration.

Indexed as

Bioprosthetic heart valvesFluid–structure interactionImmersogeometric analysisIsogeometric beams and shellsTAVRTranscatheter aortic valve replacement

Identifiers

PMID32831419
PMCPMC7442159
OpenAlexW2967378228

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.