SynthesisBMC pediatrics2020
Gender and birth weight as risk factors for anastomotic stricture after esophageal atresia repair: a systematic review and meta-analysis.
Synthesis in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Postoperative reintubation as risk factor for anastomotic stricture after congenital esophageal atresia.Pediatric surgery international · 2025Article
- Risk factors and prevention and treatment methods of anastomotic stricture after esophageal atresia repair: a literature review.Pediatric surgery international · 2025Review
- Does thoracoscopic repair of type C esophageal atresia require emergency treatment?BMC surgery · 2025Article
- The role of distance between upper and lower esophageal pouches to predict the possibility of delayed repair in children with isolated esophageal atresia.Pediatric surgery international · 2023Article
- Anastomotic stricture prediction in patients with esophageal atresia with distal fistula.Pediatric surgery international · 2023Article
- Pediatric esophageal stenoses: Challenges and new surgical device promoting tension-free esophageal anastomosis.Experimental and therapeutic medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnastomotic stricture (AS) is the most frequently occurring complication that occurs after esophageal atresia (EA) repair. Nevertheless, the pathogenesis remains primarily unknown and there is inadequate knowledge regarding the risk factors for AS. Therefore, a systematic review of the literature and a meta-analysis was performed to investigate whether gender and birth weight were risk factors for the development of AS following EA repair.
methodsThe main outcome measure was the occurrence of AS. Forest plots with odds ratios (OR) and 95% confidence intervals (CI) were generated for the outcomes. Quality assessment was performed using the Newcastle-Ottawa scale.
resultsSix studies with a total of 495 patients were included; 59% males, and 37 and 63% of the patients weighed < 2500 g and ≥ 2500 g, respectively. Male gender (OR, 0.96; 95% CI, 0.66-1.40; p = 0.82) and birth weight < 2500 g (OR, 0.74; 95% CI, 0.47-1.15; p = 0.18) did not increase the risk of AS. The majority of the included studies were retrospective cohort studies and the overall risk of bias was considered to be low to moderate.
conclusionNeither gender nor birth weight appear to have an impact on the risk of AS development following EA repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.