Evidence map›Paper›PMID 32830545›Full record

ArticleCell transplantation

Bio 3D Conduits Derived from Bone Marrow Stromal Cells Promote Peripheral Nerve Regeneration.

Hirofumi Yurie, Ryosuke Ikeguchi, Tomoki Aoyama, Mai Tanaka, Hiroki Oda, Hisataka Takeuchi, Sadaki Mitsuzawa, Maki Ando, Koichi Yoshimoto, Takashi Noguchi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  5. Review
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  7. Review
  8. Nerve regeneration using the Bio 3D nerve conduit fabricated with spheroids.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hirofumi YurieDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ryosuke IkeguchiDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0003-4525-7849
Tomoki AoyamaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Mai TanakaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hiroki OdaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hisataka TakeuchiDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Sadaki MitsuzawaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-6766-5512
Maki AndoDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Koichi YoshimotoDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takashi NoguchiDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Shizuka AkiedaCyfuse Biomedical K.K., Tokyo, Japan.
Koichi NakayamaDepartment of Regenerative Medicine and Biomedical Engineering, 13030Saga University, Saga, Japan.ORCID 0000-0002-7324-8862
Shuichi MatsudaDepartment of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kyoto University · JPSaga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously reported that a nerve conduit created from fibroblasts promotes nerve regeneration in a rat sciatic nerve model. This study aims to determine whether a nerve conduit created from bone marrow stromal cells (BMSCs) can promote nerve regeneration. Primary BMSCs were isolated from femur bone marrow of two Lewis rats, and cells at passages 4-7 were used. We created seven Bio 3D nerve conduits from BMSCs using a Bio-3D Printer. The conduits were transplanted to other Lewis rats to bridge 5-mm right sciatic nerve gaps (Bio 3D group,

Indexed as

Guided Tissue RegenerationAction PotentialsAnimalsBiomechanical PhenomenaCell SurvivalCell TrackingMaleMesenchymal Stem CellsMusclesNerve RegenerationOrgan SizePeripheral NervesRats, Inbred Lewbio 3D printerbone marrow stromal cellsnerve conduitnerve regenerationperipheral nerve

Identifiers

PMID32830545
PMCPMC7784509
OpenAlexW3080157245

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.