Evidence map›Paper›PMID 32830544›Full record

ArticleCell transplantation

Silibinin Promotes Cell Proliferation Through Facilitating G1/S Transitions by Activating Drp1-Mediated Mitochondrial Fission in Cells.

Yanting You, Liqian Chen, Yifen Wu, Ming Wang, Hanqi Lu, Xinghong Zhou, Huaxi Liu, Zixuan Fu, Qiuxing He, Jinying Ou and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Yanting YouDepartment of Traditional Chinese Medicine, 70570Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.ORCID 0000-0001-9511-9538
Liqian ChenSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Yifen WuDepartment of Oncology, Affiliated Dongguan People's Hospital, 70570Southern Medical University, Guangzhou, Guangdong, China.
Ming WangDepartment of Traditional Chinese Medicine, 70570Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Hanqi LuSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Xinghong ZhouSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Huaxi LiuSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Zixuan FuSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Qiuxing HeSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Jinying OuTraditional Chinese Pharmacological Laboratory, School of Traditional Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Xiuqiong FuSchool of Chinese Medicine, 26679Hong Kong Baptist University, Hong Kong, China.
Yanyan LiuDepartment of Traditional Chinese Medicine, 70570Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Hiuyee KwanSchool of Chinese Medicine, 26679Hong Kong Baptist University, Hong Kong, China.
Donghui LiangDepartment of Traditional Chinese Medicine, 70570Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China.
Xiaoshan ZhaoSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
Jiaojiao DaiSyndrome Laboratory of Integrated Chinese and Western Medicine, School of Chinese Medicine, 70570Southern Medical University, Guangzhou, Guangdong, China.
TCM-Intigrated Cancer Center of Southern Medical University · CNZhujiang Hospital · CNHong Kong Baptist University · HKSouthern Medical University · CNThird Affiliated Hospital of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart, liver, and kidney, which are known as the essential organs for metabolism, possess the unique ability to regulate the proliferation function of the body against injury. Silibinin (SB), a natural polyphenolic flavonoid extracted from traditional herb

Indexed as

Cell LineCell ProliferationDynaminsEpithelial CellsG1 PhaseHepatocytesHumansKidney TubulesMitochondriaMitochondrial DynamicsSilybinS PhaseDNM1L protein, humanDynaminsSilybindynamin-related protein 1G1/S cell cyclemitochondrial fissionsilibinin

Identifiers

PMID32830544
PMCPMC7563805
OpenAlexW3080515734

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.