Evidence map›Paper›PMID 32830538›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Expression of

Hirofumi Watanabe, Robert L Paxton, Matthew R Tolerico, Vidya K Nagalakshmi, Shinji Tanaka, Mark D Okusa, Shin Goto, Ichiei Narita, Seiji Watanabe, Maria Luisa S Sequeira-Lοpez and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Krüppel-like factor 2 regulates renin expression in mature juxtaglomerular cells.American journal of physiology. Renal physiology · 2026
    Article
  3. Article
  4. Article
  5. The Rayleigh Quotient and Contrastive Principal Component Analysis I.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. RIPK4 promotes oxidative stress and ferroptotic death through the downregulation of ACSM1.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Impact of renal tubularFrontiers in molecular biosciences · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Hirofumi WatanabeDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.ORCID 0000-0003-0657-5385
Robert L PaxtonDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
Matthew R TolericoDepartment of Biology, University of Virginia, Charlottesville, Virginia.
Vidya K NagalakshmiDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
Shinji TanakaDivision of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia, Charlottesville, Virginia.
Mark D OkusaDivision of Nephrology and Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia, Charlottesville, Virginia.
Shin GotoDivision of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Ichiei NaritaDivision of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Seiji WatanabeDepartment of Pediatrics, Izu Medical and Welfare Center, Shizuoka, Japan.
Maria Luisa S Sequeira-LοpezDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
R Ariel GomezDepartment of Pediatrics, Child Health Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
University of Virginia · USNiigata University · JPShizuoka Medical Center · JP

Funding

Single-Cell Epigenomics, Transcriptomics, and Bioinformatics CoreP50DK096373 · NIDDK · UNIVERSITY OF VIRGINIA · PI ROBERTO Ariel GOMEZ · 2012 to 2026
$13.8M
Sphingolipids in Acute Kidney Injury and Disease ProgressionR01DK085259 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2010 to 2023
$5.0M
Neuroimmune Regulation of Acute Kidney InjuryR01DK123248 · NIDDK · UNIVERSITY OF VIRGINIA · PI Mark Douglas Okusa · 2019 to 2026
$3.3M
Plasticity of renin cells in the kidney vasculatureR01DK116718 · NIDDK · UNIVERSITY OF VIRGINIA · PI GOMEZ, ROBERTO ARIEL · 2018 to 2022
$2.8M
Renin cell identity and blood pressure homeostasisR01HL148044 · NHLBI · UNIVERSITY OF VIRGINIA · PI SEQUEIRA-LOPEZ, MARIA LUISA SOLEDAD · 2020 to 2023
$2.7M
Ultrasound for Non-Invasive Prevention of Acute Kidney InjuryR01DK105133 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2015 to 2019
$2.4M
Fate of the kidney vasculature during partial neonatal ureteral obstructionR01DK116196 · NIDDK · UNIVERSITY OF VIRGINIA · PI SEQUEIRA-LOPEZ, MARIA LUISA SOLEDAD · 2018 to 2021
$1.5M
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 1R01 DK085259HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK 096373HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) HL 148044HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P50 DK 096373HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01 DK 116196HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01 DK 116718NHLBI NIH HHS R01 HL148044NIDDK NIH HHS P50 DK096373NIDDK NIH HHS R01 DK085259NIDDK NIH HHS R01 DK105133NIDDK NIH HHS R01 DK116196NIDDK NIH HHS R01 DK116718NIDDK NIH HHS R01 DK123248
6 · The paper itself

Abstract

The acyl-CoA synthetase medium-chain family member 2 (

Indexed as

Acute Kidney InjuryAnimalsCoenzyme A LigasesDisease Models, AnimalEpithelial CellsFibrosisGene Expression Regulation, DevelopmentalGene Expression Regulation, EnzymologicHumansIntegrin beta1Kidney Tubules, ProximalMaleMice, Inbred C57BLMice, KnockoutMitochondrial ProteinsRenal Insufficiency, ChronicACSM2A protein, humanAcsm2 protein, mouseCoenzyme A LigasesIntegrin beta1Itgb1 protein, mouseMitochondrial ProteinsReninacute kidney injuryacyl-CoA synthetasechronic kidney diseaseepigeneticsfatty acid oxidationproximal tubules

Identifiers

PMID32830538
PMCPMC7642889
OpenAlexW3080656836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.