Evidence map›Paper›PMID 32830486›Full record

ArticleACS applied materials & interfaces2020

Size-Tunable Metal-Organic Framework-Coated Magnetic Nanoparticles for Enzyme Encapsulation and Large-Substrate Biocatalysis.

Qiaobin Li, Yanxiong Pan, Hui Li, Lina Alhalhooly, Yue Li, Bingcan Chen, Yongki Choi, Zhongyu Yang

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. One-pot encapsulation of lactate dehydrogenase and FeFrontiers in bioengineering and biotechnology · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qiaobin LiDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID http://orcid.org/0000-0002-0206-1515
Yanxiong PanDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58102, United States.
Hui LiDepartment of Plant Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.
Lina AlhalhoolyDepartment of Physics, North Dakota State University, Fargo, North Dakota 58102, United States.
Yue LiDepartment of Chemistry, University of Southern California, Los Angeles California 90089, United States.
Bingcan ChenDepartment of Plant Sciences, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID http://orcid.org/0000-0002-4989-547X
Yongki ChoiDepartment of Physics, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID http://orcid.org/0000-0001-8890-8344
Zhongyu YangDepartment of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58102, United States.ORCID http://orcid.org/0000-0002-3018-3608
North Dakota State University · USUniversity of Southern California · US

Funding

Developing a hybrid biomolecule nano-circuit approach for observing and manipulating single protein dynamicsR15GM122063 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI CHOI, YONGKI · 2016 to 2016
$424k
NIGMS NIH HHS R15 GM122063
6 · The paper itself

Abstract

Immobilizing enzymes on nanoparticles (NPs) enhances the cost-efficiency of biocatalysis; however, when the substrates are large, it becomes difficult to separate the enzyme@NP from the products while avoiding leaching or damage of enzymes in the reaction medium. Metal-organic framework (MOF)-coated magnetic NPs (MNPs) offer efficient magnetic separation and enhanced enzyme protection; however, the involved enzymes/substrates have to be smaller than the MOF apertures. A potential solution to these challenges is coprecipitating metal/ligand with enzymes on the MNP surface, which can partially bury (protect) the enzyme below the composite surface while exposing the rest of the enzyme to the reaction medium for catalysis of larger substrates. Here, to prove this concept, we show that using Ca

Indexed as

BiocatalysisCalciumEnzymes, ImmobilizedMagnetite NanoparticlesMetal-Organic FrameworksMuramidaseParticle SizePhthalic AcidsSurface PropertiesCalciumEnzymes, ImmobilizedMagnetite NanoparticlesMetal-Organic FrameworksMuramidasePhthalic Acidsterephthalic acidaqueous-phase one-pot synthesisCaBDC MOFenzyme immobilizationmagnetic nanoparticle/metal−organic framework (MNP/MOF)size-tunable composites

Identifiers

PMID32830486
PMCPMC7501215
OpenAlexW3080428105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.