Evidence map›Paper›PMID 32830423›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Metal-Templated Design of Chemically Switchable Protein Assemblies with High-Affinity Coordination Sites.

Albert Kakkis, Derek Gagnon, Julian Esselborn, R David Britt, F Akif Tezcan

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Simulating Metal-Imidazole Complexes.Journal of chemical theory and computation · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Protein Assembly by Design.Chemical reviews · 2021
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Albert KakkisDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0001-6225-7352
Derek GagnonDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0003-1737-6365
Julian EsselbornDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0002-3499-8417
R David BrittDepartment of Chemistry, University of California, Davis, 1 Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0003-0889-8436
F Akif TezcanDepartment of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.ORCID 0000-0002-4733-6500

Funding

Supplement:Spectroscopy Investigations of Metalloenzyme MechanismsR35GM126961 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI R. David Britt · 2018 to 2026
$3.7M
Design and Evolution of Metal-Based Functions in Supramolecular Protein ScaffoldsR01GM138884 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TEZCAN, F. AKIF · 2020 to 2025
$2.0M
Chemistry-Biology Interfaces at UCSDT32GM146648 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Michael D. Burkart, Alexis C. Komor · 2022 to 2026
$876k
Chemical Biology Interfaces at UC San DiegoT32GM112584 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BURKART, MICHAEL D. · 2015 to 2019
$729k
NIGMS NIH HHS GM138884NIGMS NIH HHS R01 GM138884NIGMS NIH HHS R35 GM126961NIGMS NIH HHS T32 GM112584NIGMS NIH HHS T32GM112584NIGMS NIH HHS T32 GM146648
6 · The paper itself

Abstract

To mimic a hypothetical pathway for protein evolution, we previously tailored a monomeric protein (cyt cb

Indexed as

Hydrophobic and Hydrophilic InteractionsMetalloproteinsMetals, HeavyModels, MolecularMetalloproteinsMetals, Heavybioinorganic chemistrymetalloproteinsprotein designprotein structuressupramolecular chemistry

Identifiers

PMID32830423
PMCPMC7983065

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.