ArticleInternational journal of epidemiology2020
Gestational weight gain, birthweight and early-childhood obesity: between- and within-family comparisons.
Article in International journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 24 citations in OpenAlex.
- Article
- Evidence for a perinatal origin of childhood obesity: a systematic review and meta-analysis of risk and protective factors.Osong public health and research perspectives · 2026Article
- Growth Recovery After Fetal Growth Restriction: A 10-Year Follow-Up of Term-Born Children.Nutrients · 2026Observational
- Impact of maternal body mass index (BMI) and gestational weight gain on offspring's weight and BMI z-scores across the first 8 years of life.Clinical obesity · 2025Article
- Early Roots of Childhood Obesity: Risk Factors, Mechanisms, and Prevention Strategies.International journal of molecular sciences · 2025Review
- Theoretical Behavior Substitutions during the 24-h Day in Pregnancy and Infant Growth Outcomes.Medicine and science in sports and exercise · 2025Article
- Family support and motivational factors in weight loss among children and adolescents-a cross-sectional study.Frontiers in nutrition · 2025Article
- Maternal body mass index, gestational weight gain, and early childhood growth: A register-based cohort study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Gaps in the usage and reporting of multiple imputation for incomplete data: findings from a scoping review of observational studies addressing causal questions.BMC medical research methodology · 2024Article
- Maternal weight and its association with risk of overweight in offspring: a trajectory analysis from a birth cohort in China.World journal of pediatrics : WJP · 2024Article
- Pregnancy health in a multi-state U.S. population of systemically underserved patients and their children: PROMISE cohort design and baseline characteristics.BMC public health · 2024Article
- Article
- Article
- The Uterine Environment and Childhood Obesity Risk: Mechanisms and Predictions.Current nutrition reports · 2023Review
- Trends in Gestational Weight Gain in Louisiana, March 2019 to March 2022.JAMA network open · 2023Article
- Developmental origins of adult diseases.Medical review (2021) · 2022Review
- Childhood obesity and adverse cardiometabolic risk in large for gestational age infants and potential early preventive strategies: a narrative review.Pediatric research · 2022Review
- The association between maternal pre-pregnancy BMI, gestational weight gain and child adiposity: A racial-ethnically diverse cohort of children.Pediatric obesity · 2022Article
- Relationship between caesarean section delivery and risk of overweight/obesity among children aged 6-23 months in the Tamale Metropolis of Ghana.Journal of nutritional science · 2022Article
- Having siblings promotes a more healthy weight status-Whereas only children are at greater risk for higher BMI in later childhood.PloS one · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAssociations of excessive gestational weight gain (GWG) with greater birthweight and childhood obesity may be confounded by shared familial environment or genetics. Sibling comparisons can minimize variation in these confounders because siblings grow up in similar environments and share the same genetic predisposition for weight gain.
methodsWe identified 96 289 women with live births in 2008-2014 at Kaiser Permanente Northern California. Fifteen percent of women (N = 14 417) had at least two births during the study period for sibling analyses. We assessed associations of GWG according to the Institute of Medicine (IOM) recommendations with birthweight and obesity at age 3 years, using conventional analyses comparing outcomes between mothers and sibling analyses comparing outcomes within mothers, which control for stable within-family unmeasured confounders such as familial environment and genetics. We used generalized estimating-equations and fixed-effects models.
resultsIn conventional analyses, GWG above the IOM recommendations was associated with 88% greater odds of large-for-gestational age birthweight [95% confidence interval (CI): 1.80, 1.97] and 30% greater odds of obesity at 3 years old (95% CI: 1.24, 1.37) compared with GWG within the IOM recommendations. In sibling analyses, GWG above the IOM recommendations was also associated with greater odds of large-for-gestational age [odds ratio (OR): 1.36; 95% CI: 1.20, 1.54], but was not associated with obesity at 3 years old (OR = 0.98; 95% CI: 0.84, 1.15).
conclusionsGWG likely has a direct impact on birthweight; however, shared environmental and lifestyle factors within families may play a larger role in determining early-childhood weight status and obesity risk than GWG.
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