Evidence map›Paper›PMID 32830192›Full record

ArticleJournal of microbiology and biotechnology2020

Fermentation and Metabolic Pathway Optimization to De Novo Synthesize (2S)-Naringenin in

Shenghu Zhou, Tingting Hao, Jingwen Zhou

Abstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. ACS synthetic biology · 2025
    Article
  4. Review
  5. EngineeringJournal of microbiology and biotechnology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shenghu ZhouNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu 214122, P.R. China.
Tingting HaoNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu 214122, P.R. China.
Jingwen ZhouNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu 214122, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids have diverse biological functions in human health. All flavonoids contain a common 2-phenyl chromone structure (C6-C3-C6) as a scaffold. Hence, in using such a scaffold, plenty of highvalue-added flavonoids can be synthesized by chemical or biological catalyzation approaches. (2S)-Naringenin is one of the most commonly used flavonoid scaffolds. However, biosynthesizing (2S)-naringenin has been restricted not only by low production but also by the expensive precursors and inducers that are used. Herein, we established an induction-free system to de novo biosynthesize (2S)-naringenin in

Indexed as

Biosynthetic PathwaysFermentationAnti-Ulcer AgentsBatch Cell Culture TechniquesBioreactorsCulture MediaEscherichia coliEstrogen AntagonistsFlavanonesFlavonoidsHydrogen-Ion ConcentrationMetabolic EngineeringTemperatureTyrosineAnti-Ulcer AgentsCulture MediaEstrogen AntagonistsFlavanonesFlavonoidsnaringeninTyrosinedynamic regulationflavonoidsL-tyrosinep-coumaric acidtemperature-shift

Identifiers

PMID32830192
PMCPMC9728391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.