Evidence map›Paper›PMID 32830177›Full record

ArticleInternal medicine (Tokyo, Japan)2021

Anti-MuSK Positive Myasthenia Gravis with Anti-Lrp4 and Anti-titin Antibodies.

Rika Yamashita, Mikito Shimizu, Kousuke Baba, Goichi Beck, Makoto Kinoshita, Tatsusada Okuno, Osamu Higuchi, Hideki Mochizuki

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rika YamashitaDepartment of Neurology, Osaka University Hospital, Japan.
Mikito ShimizuDepartment of Neurology, Osaka University Hospital, Japan.
Kousuke BabaDepartment of Neurology, Osaka University Hospital, Japan.
Goichi BeckDepartment of Neurology, Osaka University Hospital, Japan.
Makoto KinoshitaDepartment of Neurology, Osaka University Hospital, Japan.
Tatsusada OkunoDepartment of Neurology, Osaka University Hospital, Japan.
Osamu HiguchiDepartment of Clinical Research, Nagasaki Kawatana Medical Center, Japan.
Hideki MochizukiDepartment of Neurology, Osaka University Hospital, Japan.
Osaka University Hospital · JPNagasaki Kawatana Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to muscle nicotinic acetylcholine receptor (AChR) and muscle-specific kinase (MuSK), low-density lipoprotein receptor (Lrp4) has recently been discovered to be a novel target antigen among patients with seronegative myasthenia gravis (MG). We herein report the findings of a 62-year-old patient who showed positivity for anti-MuSK, anti-Lrp4, and anti-titin antibodies. The patient developed MG crisis following a 10-year history of intermittent double vision with ptosis, and a 7-year history of dropped head. Our detailed clinical, laboratory, and therapeutic descriptions highlight its unique characteristics of anti-MuSK-antibody positive MG accompanied by anti-Lrp4 and anti-titin antibodies.

Indexed as

Myasthenia GravisReceptors, NicotinicAutoantibodiesConnectinHumansLDL-Receptor Related ProteinsMiddle AgedReceptors, LDLAutoantibodiesConnectinLDL-Receptor Related ProteinsReceptors, LDLReceptors, Nicotinicanti-Lrp4 antibodyanti-MuSK antibodyanti-titin antibodymyasthenia gravissteroid pulse therapy

Identifiers

PMID32830177
PMCPMC7835456
OpenAlexW3080223519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.