Trial reportThe British journal of ophthalmology2021
12-month randomised trial of 360° and 180° Schlemm's canal incisions in suture trabeculotomy ab interno for open-angle glaucoma.
Trial report in The British journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Minimally invasive trabecular meshwork surgery for open-angle glaucoma.The Cochrane database of systematic reviews · 2026Pooled it
- Preliminary Outcomes of iStent Inject vs Kahook Dual Blade Goniotomy Combined With Phacoemulsification: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026Trial
- Outcomes of a randomised trial comparing 360° and 180° schlemm's canal incisions in suture trabeculotomy ab interno for primary open-angle glaucoma and exfoliation glaucoma: a 5-year analysis.Japanese journal of ophthalmology · 2025Trial
- Impact of Small Incision Reduction and Suture Linked with Functional Appliance of Sufferers with Irrecoverable TMJ Anterior Disc Displacement.Computational and mathematical methods in medicine · 2022Trial
- Outcomes of phacoemulsification combined with ab interno trabeculotomy: stratified by incision extent, glaucoma severity, and baseline number of medications.Eye (London, England) · 2026Article
- Bent ab interno needle goniotomy versus gonioscopy-assisted transluminal trabeculotomy in primary open angle glaucoma: a randomised clinical trial, 24-month outcomes.Eye (London, England) · 2026Article
- Intraocular pressure spikes after trabecular meshwork strip peeling during hemi-GATT.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Management and outcomes of primary open-angle glaucoma.Journal of family medicine and primary care · 2026Review
- Comparison of the effectiveness between propensity score-matched trabecular micro-bypass stent versus ab interno trabeculotomy.Japanese journal of ophthalmology · 2026Article
- Trabecular Meshwork-Based MIGS: Efficacy, Technique Variability, and Wound Healing-A Comprehensive Review.Journal of clinical medicine · 2026Review
- Comparison of outcomes of circumferential versus hemi-gonioscopy-assisted transluminal trabeculotomy in primary open-angle glaucoma: 24-Month results.International ophthalmology · 2026Article
- Two-year outcomes of modified external suture trabeculotomy for Chinese open-angle glaucoma patients.Frontiers in medicine · 2026Article
- A Systematic and Narrative Review of Safety and Complications in Minimally Invasive Glaucoma Surgery (MIGS) Between 2014-2024.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Efficacy and safety of 360º and 180º gonioscopy-assisted transluminal trabeculotomy in combination with phacoemulsification in patients with open-angle glaucoma: a retrospective case-control study.BMC ophthalmology · 2025Article
- Clinical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy in Eyes After Failed Trabeculectomy.Journal of clinical medicine · 2025Article
- Analysis of surgical outcomes and risk factors after gonioscopy-assisted transluminal trabeculotomy.BMC ophthalmology · 2025Observational
- Ab Interno Goniotomy/Goniectomy TechniquesTurkish journal of ophthalmology · 2025Review
- Surgical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Primary and Secondary Open- and Closed-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2025Article
- Comparison of Standalone Tanito Microhook Trabeculotomy Between Unilateral and Bilateral Incision Groups.Journal of clinical medicine · 2025Article
- Short-term outcomes of Tanito microhook ab interno trabeculotomy combined with phacoemulsification in primary open-angle glaucoma - A pilot study.Indian journal of ophthalmology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsTo perform a 12-month comparison between the different extents and locations of Schlemm's canal incisions during suture trabeculotomy ab interno for open-angle glaucoma (OAG).
methodsThis is a prospective, single-centre, three-arm randomised trial. A total of 99 eyes of 99 patients were randomly assigned to one of three groups: the 360° incision group (n=34), the upper-180° incision group (n=34) and the lower-180° incision group (n=31). Intraocular pressure (IOP), number of medications and complications were evaluated until 12 months after surgery. Surgical success (with or without medication) was defined as IOP ≤21 mmHg and ≥20% IOP reduction (criterion A) or IOP ≤15 mmHg and ≥20% IOP reduction (criterion B).
resultsThe mean IOP (±SD) in all eyes was reduced from 18.6 (5.9) mmHg with 3.1 (1.1) medications to 13.7 (3.4) mmHg (20.8% reduction;
conclusionsThe different extents and locations of Schlemm's canal incisions during suture trabeculotomy ab interno for OAG, including the 360° incision, the upper-180° incision and the lower-180° incision, do not affect both the IOP reduction and the medications throughout 12 months of follow-up. TRIAL REGISTRATION NUMBER: UMIN000021169.
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