Evidence map›Paper›PMID 32829859›Full record

ReviewCarbohydrate polymers2020

A review for natural polysaccharides with anti-pulmonary fibrosis properties, which may benefit to patients infected by 2019-nCoV.

Rui-Rong Chen, Ya-Jun Li, Jun-Jia Chen, Chuan-Li Lu

Open access · greenAbstract readReview
In one paragraph

Review in Carbohydrate polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rui-Rong ChenGuangdong Key Lab of Sugarcane Improvement & Bio-Refinery, Guangdong Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute), Guangdong Academy of Sciences, Guangzhou, 510316, People's Republic of China.
Ya-Jun LiGuangdong Key Lab of Sugarcane Improvement & Bio-Refinery, Guangdong Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute), Guangdong Academy of Sciences, Guangzhou, 510316, People's Republic of China.
Jun-Jia ChenGuangdong Key Lab of Sugarcane Improvement & Bio-Refinery, Guangdong Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute), Guangdong Academy of Sciences, Guangzhou, 510316, People's Republic of China. Electronic address: gzcsircjj@163.com.
Chuan-Li LuGuangdong Key Lab of Sugarcane Improvement & Bio-Refinery, Guangdong Bioengineering Institute (Guangzhou Sugarcane Industry Research Institute), Guangdong Academy of Sciences, Guangzhou, 510316, People's Republic of China. Electronic address: luyixiao-0707@163.com.
Guangdong Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary fibrosis (PF) is a lung disease with highly heterogeneous and mortality rate, but its therapeutic options are now still limited. Corona virus disease 2019 (COVID-19) has been characterized by WHO as a pandemic, and the global number of confirmed COVID-19 cases has been more than 8.0 million. It is strongly supported for that PF should be one of the major complications in COVID-19 patients by the evidences of epidemiology, viral immunology and current clinical researches. The anti-PF properties of naturally occurring polysaccharides have attracted increasing attention in last two decades, but is still lack of a comprehensively understanding. In present review, the resources, structural features, anti-PF activities, and underlying mechanisms of these polysaccharides are summarized and analyzed, which was expected to provide a scientific evidence supporting the application of polysaccharides for preventing or treating PF in COVID-19 patients.

Indexed as

BetacoronavirusPandemicsAnimalsAntioxidantsBiological ProductsBleomycinCoronavirus InfectionsCOVID-19Disease Models, AnimalDrug Evaluation, PreclinicalForkhead Box Protein O3FungiHeterogeneous Nuclear Ribonucleoprotein D0HumansMacrophagesMedicine, Chinese TraditionalAntioxidantsBiological ProductsBleomycinDANCR long noncoding RNA, humanForkhead Box Protein O3FOXO3 protein, humanHeterogeneous Nuclear Ribonucleoprotein D0HNRNPD protein, humanPolysaccharidesRNA, Long NoncodingSmad2 ProteinSMAD2 protein, humanSmad3 ProteinSMAD3 protein, humanTransforming Growth Factor beta1Corona virus disease 2019MechanismsPolysaccharidesPulmonary fibrosis

Identifiers

PMID32829859
PMCPMC7340049
OpenAlexW3038558005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.