Evidence map›Paper›PMID 32829715›Full record

ArticleParasitology2020

First report of

A Rojas, H Salant, D Yasur-Landau, H Tsarfati, G Baneth

Abstract readCase Reports
In one paragraph

Article in Parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Zoonotic Ocular Onchocercosis byThe Yale journal of biology and medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A RojasKoret School of Veterinary Medicine, Hebrew University of Jerusalem, P.O. Box 12, Rehovot7610001, Israel.ORCID 0000-0003-2007-7198
H SalantKoret School of Veterinary Medicine, Hebrew University of Jerusalem, P.O. Box 12, Rehovot7610001, Israel.
D Yasur-LandauDivision of Parasitology, Kimron Veterinary Institute, P.O. Box 12, 50250, Bet Dagan, Israel.
H TsarfatiOpthalmic Veterinary Clinic, Neve Monosson, Israel.
G BanethKoret School of Veterinary Medicine, Hebrew University of Jerusalem, P.O. Box 12, Rehovot7610001, Israel.ORCID 0000-0002-7549-1305

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Onchocerca lupi is a parasitic filarioid and the causative agent of canine ocular onchocercosis, a zoonotic disease of domestic dogs with sporadic reports in humans. A 13-year-old dog with no travel history outside of Israel was presented to an ophthalmology veterinary clinic in Israel with severe right ocular and periocular disease. After surgical exploration, thin helminths were removed from the dorsal sclera of the eye and identified as Onchocerca lupi by polymerase chain reaction according to the cytochrome c oxidase subunit I (cox1), reduced nicotinamide adenine dinucleotide dehydrogenase subunit 5 (nad5) and 12S rRNA genes. Phylogenetic trees and haplotype networks of the cox1 and nad5 genes confirmed the circulation of two genotypes: genotype 1 with worms from dogs, cats and humans from both the Old and New Worlds, and genotype 2 with specimens from Portugal and Spain. The Israeli sequences clustered in genotype 1 and were identical to O. lupi from the USA. Evidence of two genotypes separated geographically sheds light on the phylogeography and evolution of this zoonotic pathogen, and suggests a diverse pathology observed in different regions of the world.

Indexed as

GenotypeAnimalsCat DiseasesCatsDog DiseasesDogsHelminth ProteinsHumansIsraelOnchocercaOnchocerciasis, OcularPhylogenyHelminth ProteinsCatdoggenotypeshumanIsraelOnchocerca lupizoonoses

Identifiers

PMID32829715
PMCPMC10317758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.