ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
On folding morphogenesis, a mechanical problem.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Biophysics of lumen morphogenesis.Development (Cambridge, England) · 2026Review
- Investigating active dynamics of contractile actomyosin gels with micro particle image velocimetry (micro-PIV) analysis.Scientific reports · 2026Article
- Article
- Cell Contractile Force-Mediated Morphogenetic Tissue Engineering via 4D Printed Degradable Hydrogel Scaffolds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Convergent flow-mediated mesenchymal force drives embryonic foregut constriction and splitting.Nature communications · 2025Article
- Convergent flow-mediated mesenchymal force drives embryonic foregut constriction and splitting.bioRxiv : the preprint server for biology · 2025Article
- A multi-tiered mechanical mechanism shapes the early neural plate.Nature communications · 2025Article
- The Mechanics of Building Functional Organs.Cold Spring Harbor perspectives in biology · 2025Review
- EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues in Drosophila melanogaster.Developmental cell · 2025Article
- Cell proliferation and Notch signaling coordinate the formation of epithelial folds in the Drosophila leg.Development (Cambridge, England) · 2024Article
- Self-assembled active actomyosin gels spontaneously curve and wrinkle similar to biological cells and tissues.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues.bioRxiv : the preprint server for biology · 2023Article
- Forceful patterning: theoretical principles of mechanochemical pattern formation.EMBO reports · 2023Review
- How dynamic prestress governs the shape of living systems, from the subcellular to tissue scale.Interface focus · 2022Review
- Signaling in the crowded cell.Current opinion in structural biology · 2021Review
- Pinching and pushing: fold formation in the Drosophila dorsal epidermis.Biophysical journal · 2021Article
- Contemporary morphogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Tissue folding is a fundamental process that sculpts a simple flat epithelium into a complex three-dimensional organ structure. Whether it is the folding of the brain, or the looping of the gut, it has become clear that to generate an invagination or a fold of any form, mechanical asymmetries must exist in the epithelium. These mechanical asymmetries can be generated locally, involving just the invaginating cells and their immediate neighbours, or on a more global tissue-wide scale. Here, we review the different mechanical mechanisms that epithelia have adopted to generate folds, and how the use of precisely defined mathematical models has helped decipher which mechanisms are the key driving forces in different epithelia. This article is part of a discussion meeting issue 'Contemporary morphogenesis'.
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