ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
Cell intercalation in a simple epithelium.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Article
- Supracellular Mechanics and Counter-Rotational Bilateral Flows Orchestrate Posterior Morphogenesis.bioRxiv : the preprint server for biology · 2025Article
- Review
- Epithelial Layer Fluidization by Curvature-Induced Unjamming.Physical review letters · 2025Article
- Article
- Article
- Robust statistical properties of T1 transitions in a multi-phase field model of cell monolayers.Scientific reports · 2023Article
- Random nature of epithelial cancer cell monolayers.Journal of the Royal Society, Interface · 2022Article
- Caenorhabditis elegans LET-413 Scribble is essential in the epidermis for growth, viability, and directional outgrowth of epithelial seam cells.PLoS genetics · 2021Article
- Rosette morphology in zona glomerulosa formation and function.Molecular and cellular endocrinology · 2021Review
- Mechanical Feedback Control for Multicellular Tissue Size Maintenance: A Minireview.Frontiers in cell and developmental biology · 2021Review
- Elasticity, Stability, and Quasioscillations of Cell-Cell Junctions in Solid Confluent Epithelia.Biophysical journal · 2020Article
- Contemporary morphogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell intercalation is a key topological transformation driving tissue morphogenesis, homeostasis and diseases such as cancer cell invasion. In recent years, much work has been undertaken to better elucidate the fundamental mechanisms controlling intercalation. Cells often use protrusions to propel themselves in between cell neighbours, resulting in topology changes. Nevertheless, in simple epithelial tissues, formed by a single layer of densely packed prism-shaped cells, topology change takes place in an astonishing fashion: cells exchange neighbours medio-laterally by conserving their apical-basal architecture and by maintaining an intact epithelial layer. Medio-lateral cell intercalation in simple epithelia is thus an exemplary case of both robustness and plasticity. Interestingly, in simple epithelia, cells use a combinatory set of mechanisms to ensure a topological transformation at the apical and basal sides. This article is part of the discussion meeting issue 'Contemporary morphogenesis'.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.