Evidence map›Paper›PMID 32829256›Full record

ArticleJournal of photochemistry and photobiology. B, Biology2020

Laser irradiated phenothiazines: New potential treatment for COVID-19 explored by molecular docking.

Ana-Maria Udrea, Speranta Avram, Simona Nistorescu, Mihail-Lucian Pascu, Mihaela Oana Romanitan

Open access · greenAbstract read
In one paragraph

Article in Journal of photochemistry and photobiology. B, Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Psychotropic drug repurposing for COVID-19: A Systematic Review and Meta-Analysis.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2023
    Pooled it
  2. Spectroscopic Analysis of the TiOInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Repositioning of histamine HEuropean journal of pharmacology · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ana-Maria UdreaLaser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele, Ilfov, Romania; Department of Anatomy, Animal Biology, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania.
Speranta AvramDepartment of Anatomy, Animal Biology, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania.
Simona NistorescuLaser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele, Ilfov, Romania; Department of Botany and Microbiology, Faculty of Biology, University of Bucharest, Bucharest, Romania.
Mihail-Lucian PascuLaser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele, Ilfov, Romania; Faculty of Physics, University of Bucharest, Magurele, Romania. Electronic address: mihai.pascu@inflpr.ro.
Mihaela Oana RomanitanStockholm South General Hospital, Department of Emergency internal medicine and Neurology, Karolinska Institute Stroke Research Network at Södersjukhuset, 118 83 Stockholm, Sweden.
National Institute for Laser Plasma and Radiation Physics · ROUniversity of Bucharest · ROStockholm South General Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The worldwide infection with the new Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) demands urgently new potent treatment(s). In this study we predict, using molecular docking, the binding affinity of 15 phenothiazines (antihistaminic and antipsychotic drugs) when interacting with the main protease (M

Indexed as

BetacoronavirusAntiviral AgentsCoronavirus 3C ProteasesCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentCysteine EndopeptidasesHost Microbial InteractionsHumansLasers, Solid-StateMolecular Docking SimulationPandemicsPhenothiazinesPhotochemical ProcessesPneumonia, ViralSARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesCysteine EndopeptidasesPhenothiazinesViral Nonstructural ProteinsCOVID-19Laser irradiated phenothiazinesMolecular dockingSARS-CoV-2

Identifiers

PMID32829256
PMCPMC7428740
OpenAlexW3048569212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.