Evidence map›Paper›PMID 32828614›Full record

ArticleJournal of the American College of Cardiology2020

Management and Outcomes of Patients With STEMI During the COVID-19 Pandemic in China.

Dingcheng Xiang, Xin Xiang, Wei Zhang, Shaodong Yi, Jinxia Zhang, Xiaolong Gu, Yawei Xu, Kai Huang, Xi Su, Bo Yu and 4 more

Abstract read
In one paragraph

Article in Journal of the American College of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed, 6 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Dingcheng XiangDepartment of Cardiology, General Hospital of Southern Theatre Command of PLA, Guangzhou, China. Electronic address: dcxiang@foxmail.com.
Xin XiangGraduate School of Arts and Sciences, Harvard University, Cambridge, Massachusetts.
Wei ZhangDepartment of Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Shaodong YiDepartment of Cardiology, General Hospital of Southern Theatre Command of PLA, Guangzhou, China.
Jinxia ZhangDepartment of Cardiology, General Hospital of Southern Theatre Command of PLA, Guangzhou, China.
Xiaolong GuDepartment of Cardiology, General Hospital of Southern Theatre Command of PLA, Guangzhou, China.
Yawei XuDepartment of Cardiology, 10th Hospital of Tongji University, Shanghai, China.
Kai HuangDepartment of Cardiology, Union Hospital of Huazhong University of Science and Technology, Wuhan, China.
Xi SuDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, China.
Bo YuDepartment of Cardiology, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
Yan WangDepartment of Cardiology, Xiamen Heart Center, Xiamen, China.
Weiyi FangDepartment of Cardiology, Shanghai Dongfang Hospital, Shanghai, China.
Yong HuoDepartment of Cardiology, Peking University First Hospital, Beijing, China. Electronic address: drhuoyong@163.com.
Junbo GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundST-segment elevation myocardial infarction (STEMI) is a fatal cardiovascular emergency requiring rapid reperfusion treatment. During the coronavirus disease-2019 (COVID-19) pandemic, medical professionals need to strike a balance between providing timely treatment for STEMI patients and implementing infection control procedures to prevent nosocomial spread of COVID-19 among health care workers and other vulnerable cardiovascular patients.

objectivesThis study evaluates the impact of the COVID-19 outbreak and China Chest Pain Center's modified STEMI protocol on the treatment and prognosis of STEMI patients in China.

methodsBased on the data of 28,189 STEMI patients admitted to 1,372 Chest Pain Centers in China between December 27, 2019 and February 20, 2020, the study analyzed how the COVID-19 outbreak and China Chest Pain Center's modified STEMI protocol influenced the number of admitted STEMI cases, reperfusion strategy, key treatment time points, and in-hospital mortality and heart failure for STEMI patients.

resultsThe COVID-19 outbreak reduced the number of STEMI cases reported to China Chest Pain Centers. Consistent with China Chest Pain Center's modified STEMI protocol, the percentage of patients undergoing primary percutaneous coronary intervention declined while the percentage of patients undergoing thrombolysis increased. With an average delay of approximately 20 min for reperfusion therapy, the rate of in-hospital mortality and in-hospital heart failure increased during the outbreak, but the rate of in-hospital hemorrhage remained stable.

conclusionsThere were reductions in STEMI patients' access to care, delays in treatment timelines, changes in reperfusion strategies, and an increase of in-hospital mortality and heart failure during the COVID-19 pandemic in China.

Indexed as

Coronavirus InfectionsInfection ControlPandemicsPercutaneous Coronary InterventionPneumonia, ViralST Elevation Myocardial InfarctionThrombolytic TherapyBetacoronavirusChinaCoronary AngiographyCOVID-19FemaleHeart FailureHospitalizationHospital MortalityHumanschest pain centerCOVID-19primary percutaneous coronary interventionST-segment elevation myocardial infarctionthrombolysis

Identifiers

PMID32828614
PMCPMC7438071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.