Evidence map›Paper›PMID 32828463›Full record

ReviewProgress in molecular biology and translational science2020

Intrinsically disordered proteins of viruses: Involvement in the mechanism of cell regulation and pathogenesis.

Pushpendra Mani Mishra, Navneet Chandra Verma, Chethana Rao, Vladimir N Uversky, Chayan Kanti Nandi

Open access · greenAbstract readReview
In one paragraph

Review in Progress in molecular biology and translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
41.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
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  12. Review
  13. Phosphorylation enables allosteric control of a viral condensate.bioRxiv : the preprint server for biology · 2025
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  14. Review
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Pushpendra Mani MishraSchool of Basic Sciences, Indian Institute of Technology, Mandi, Mandi, Himachal Pradesh, Mandi, India.
Navneet Chandra VermaSchool of Basic Sciences, Indian Institute of Technology, Mandi, Mandi, Himachal Pradesh, Mandi, India.
Chethana RaoSchool of Basic Sciences, Indian Institute of Technology, Mandi, Mandi, Himachal Pradesh, Mandi, India.
Vladimir N UverskyDepartment of Molecular Medicine and Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States; Laboratory of New Methods in Biology, Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Pushchino, Moscow Region, Russia. Electronic address: vuversky@health.usf.edu.
Chayan Kanti NandiSchool of Basic Sciences, Indian Institute of Technology, Mandi, Mandi, Himachal Pradesh, Mandi, India. Electronic address: chayan@iitmandi.ac.in.
Indian Institute of Technology Mandi · INUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrinsically disordered proteins (IDPs) possess the property of inherent flexibility and can be distinguished from other proteins in terms of lack of any fixed structure. Such dynamic behavior of IDPs earned the name "Dancing Proteins." The exploration of these dancing proteins in viruses has just started and crucial details such as correlation of rapid evolution, high rate of mutation and accumulation of disordered contents in viral proteome at least understood partially. In order to gain a complete understanding of this correlation, there is a need to decipher the complexity of viral mediated cell hijacking and pathogenesis in the host organism. Further there is necessity to identify the specific patterns within viral and host IDPs such as aggregation; Molecular recognition features (MoRFs) and their association to virulence, host range and rate of evolution of viruses in order to tackle the viral-mediated diseases. The current book chapter summarizes the aforementioned details and suggests the novel opportunities for further research of IDPs senses in viruses.

Indexed as

AnimalsCell CycleHumansIntrinsically Disordered ProteinsProteomeTropismViral ProteinsVirusesIntrinsically Disordered ProteinsProteomeViral ProteinsAggregationCell hijackingDancing proteinsIDPsMoRFsViruses

Identifiers

PMID32828463
PMCPMC7129803
OpenAlexW3015060035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.